Anne Imberty

TL;DR: The established predictive protocol is proposed to rationalize large sets of data such as glycan arrays and to help in lead discovery projects based on such high throughput technology.

TL;DR: This study provides for the first time a link between E-Cadherin, the aberrant Wnt/β-Catenin signaling, autophagy and differentiation in acute myeloid leukemia.

TL;DR: The first X‐ray structures of the wild‐type and recombinant Discoidin II in unliganded state and in complex with monosaccharides are presented and highlights the structural differentiation of the DS domain involved in many cell‐adhesion processes from the lectin activity of Dictyostelium discoidins.

TL;DR: Janus lectin this article is a chimeric bispecific lectin with two rationally oriented and distinct recognition surfaces, which is able to bind independently to both fucosylated and sialylated glycoconjugates.

TL;DR: In this paper, a fold-recognition approach was proposed to detect conserved motifs that have a direct role in the functional aspects of glycosyltransferases. But the method is not suitable for protein-protein interactions and only two structural folds have been identified among the fewer than one dozen GAs that have been crystallized.