A
Anne Imberty
Researcher at University of Grenoble
Publications - 406
Citations - 20811
Anne Imberty is an academic researcher from University of Grenoble. The author has contributed to research in topics: Lectin & Binding site. The author has an hindex of 74, co-authored 381 publications receiving 18759 citations. Previous affiliations of Anne Imberty include Bar-Ilan University & Joseph Fourier University.
Papers
More filters
Journal ArticleDOI
Single-coordinate-driving method for molecular docking: Application to modeling of guest inclusion in cyclodextrin
TL;DR: The philosophy of the newly developed approach is not only to find the best dock for the receptor-ligand(s) system, but also to describe all the important binding modes and provide a good starting point for studying the dynamics within the cavity during the docking process.
Journal ArticleDOI
Structure and Conformation of Mannoamidines by Nmr and Molecular Modeling: are They Good Transition State Mimics?
TL;DR: The conformation of two mannose-based amidines, the N-benzylmannoamidine and a pseudo (1→6) dimannoside, has been evaluated using semi-empirical AMI calculations and 1H NMR studies as mentioned in this paper.
Journal ArticleDOI
Specific Targeting of Plant and Apicomplexa Parasite Tubulin through Differential Screening Using In Silico and Assay-Based Approaches
Emmanuelle Soleilhac,Loraine Brillet-Guéguen,Loraine Brillet-Guéguen,Véronique Roussel,Renaud Prudent,Bastien Touquet,Sheena Dass,Samia Aci-Sèche,Vinod Kasam,Caroline Barette,Anne Imberty,Vincent Breton,Marylin Vantard,Dragos Horvath,Cyrille Y. Botté,Isabelle Tardieux,Sylvaine Roy,Eric Maréchal,Laurence Lafanechère +18 more
TL;DR: Dinitroaniline related and non-related compounds inhibit plant, but not mammalian tubulin assembly in vitro, and accordingly arrest A. thaliana development, highlighting the potential of novel herbicidal scaffolds in the design of urgently needed anti-parasitic drugs.
OtherDOI
Specificity and affinity studies in lectin/carbohydrate interactions
TL;DR: Lectins are ubiquitous carbohydrate-binding proteins, characterized by their specificity recognition towards complex oligosaccharides and their non-immune origin.
Journal ArticleDOI
Virtual Screening Against Carbohydrate-Binding Proteins: Evaluation and Application to Bacterial Burkholderia ambifaria Lectin.
Tamir Dingjan,Emilie Gillon,Anne Imberty,Serge Pérez,Alexander Titz,Paul A. Ramsland,Elizabeth Yuriev +6 more
TL;DR: The utility of virtual screening protocols, integrating ligand-based pharmacophore filtering and structure-based constraints, in the search for bacterial lectin inhibitors are demonstrated.