A
Anne Imberty
Researcher at University of Grenoble
Publications - 406
Citations - 20811
Anne Imberty is an academic researcher from University of Grenoble. The author has contributed to research in topics: Lectin & Binding site. The author has an hindex of 74, co-authored 381 publications receiving 18759 citations. Previous affiliations of Anne Imberty include Bar-Ilan University & Joseph Fourier University.
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A comparison and chemometric analysis of several molecular mechanics force fields and parameter sets applied to carbohydrates
Serge Pérez,Anne Imberty,Søren Balling Engelsen,Jan Gruza,Karim Mazeau,Jesús Jiménez-Barbero,Ana Poveda,Juan-Félix Espinosa,Bouke P van Eyck,Glenn P. Johnson,Alfred D. French,Marie Louise C.E Kouwijzer,Peter D.J Grootenuis,Anna Bernardi,Laura Raimondi,Hanoch Senderowitz,Viviane Durier,Gérard Vergoten,Kjeld Rasmussen +18 more
TL;DR: In this article, the results derived from a chemometric analysis (principal component analysis, PCA) give a global view of the performances of the force fields and parameter sets for carbohydrates.
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Structure and conformation of complex carbohydrates of glycoproteins, glycolipids, and bacterial polysaccharides
TL;DR: Although theoretical calculations of the conformation and stability of free oligosaccharides and of complexes with proteins can be carried out by molecular mechanics methods, the role of solvent water for these highly polar molecules continues to present computational problems.
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Structural basis for the interaction between human milk oligosaccharides and the bacterial lectin PA-IIL of Pseudomonas aeruginosa.
Stephanie Perret,Charles Sabin,Claire Dumon,Martina Pokorná,Catherine Gautier,Oxana Galanina,Shahov Ilia,Nicolai V. Bovin,Magali Nicaise,Michel Desmadril,Nechama Gilboa-Garber,Michaela Wimmerová,Edward P. Mitchell,Anne Imberty +13 more
TL;DR: This study demonstrates the specific blocking of PA-IIL, a fucose-binding lectin of the human pathogen Pseudomonas aeruginosa, by milk oligosaccharides and provides important structural information about compounds that could be of general application in new therapeutic strategies against bacterial infections.
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Current trends in the structure-activity relationships of sialyltransferases.
Magali Audry,Charlotte Jeanneau,Anne Imberty,Anne Harduin-Lepers,Philippe Delannoy,Christelle Breton +5 more
TL;DR: The observed structural and functional differences strongly suggest that these two structural superfamilies have evolved independently of the canonical glycosyltransferase folds.
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Binding sugars: from natural lectins to synthetic receptors and engineered neolectins
TL;DR: From the accumulated knowledge on protein-carbohydrate interactions, it is now possible to use nucleotide and peptide (bio)synthesis for producing new carbohydrate-binding molecules and this approach can also be addressed by boron chemistry and supra-molecular chemistry for the design of fully artificial glycosensors.