A
Annie Andrieux
Researcher at University of Grenoble
Publications - 124
Citations - 6666
Annie Andrieux is an academic researcher from University of Grenoble. The author has contributed to research in topics: Microtubule & Tubulin. The author has an hindex of 40, co-authored 122 publications receiving 5708 citations. Previous affiliations of Annie Andrieux include Commissariat à l'énergie atomique et aux énergies alternatives & Council for the Curriculum, Examinations & Assessment.
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Journal ArticleDOI
Deletion of beta 1 integrins in mice results in inner cell mass failure and peri-implantation lethality.
L E Stephens,Ann Sutherland,I V Klimanskaya,Annie Andrieux,Juanito J. Meneses,Roger A. Pedersen,Caroline H. Damsky +6 more
TL;DR: In vitro analysis showed that trophoblast function in beta 1-null peri-implantation embryos was largely normal, including expression of tissue-specific markers, and outgrowth on fibronectin- and vitronECTin-coated, although not on laminin- coated substrates, which suggests beta 1 integrins are required for normal morphogenesis of the inner cell mass.
Journal ArticleDOI
Altering the course of schizophrenia: progress and perspectives
Millan Mark,Annie Andrieux,George Bartzokis,Kristin S. Cadenhead,Paola Dazzan,Paolo Fusar-Poli,Jürgen Gallinat,Jay N. Giedd,Dennis R. Grayson,Markus Heinrichs,René S. Kahn,Marie-Odile Krebs,Marion Leboyer,David A. Lewis,Oscar Marín,Philippe Marin,Andreas Meyer-Lindenberg,Patrick D. McGorry,Philip McGuire,Michael John Owen,Paul Patterson,Akira Sawa,Michael Spedding,Peter J. Uhlhaas,Flora M. Vaccarino,Claes Wahlestedt,Daniel R. Weinberger +26 more
TL;DR: A broad-based consideration of the challenges and opportunities inherent in efforts to alter the course of schizophrenia is provided, including 'hybrid' strategies that both relieve presenting symptoms and reduce the risk of transition to schizophrenia or another psychiatric disorder.
Journal ArticleDOI
Mutations in TUBG1 , DYNC1H1 , KIF5C and KIF2A cause malformations of cortical development and microcephaly
Karine Poirier,Nicolas Lebrun,Nicolas Lebrun,Loic Broix,Loic Broix,Guoling Tian,Yoann Saillour,Yoann Saillour,Cécile Boscheron,Elena Parrini,Stéphanie Valence,Stéphanie Valence,Benjamin Saint Pierre,Benjamin Saint Pierre,Madison Oger,Madison Oger,Didier Lacombe,David Geneviève,Elena Fontana,Franscesca Darra,Claude Cances,Magalie Barth,Dominique Bonneau,Bernardo Dalla Bernadina,Sylvie Nguyen,Cyril Gitiaux,Cyril Gitiaux,Cyril Gitiaux,Philippe Parent,Vincent des Portes,Jean Michel Pedespan,Victoire Legrez,Laetitia Castelnau-Ptakine,Laetitia Castelnau-Ptakine,Patrick Nitschke,Thierry Hieu,Cécile Masson,Diana Zelenika,Annie Andrieux,Fiona Francis,Fiona Francis,Renzo Guerrini,Nicholas J. Cowan,Nadia Bahi-Buisson,Nadia Bahi-Buisson,Nadia Bahi-Buisson,Jamel Chelly,Jamel Chelly +47 more
TL;DR: The discovery of multiple pathogenic missense mutations in TUBG1, DYNC1H1 and KIF2A, as well as a single germline mosaic mutation in KIF5C, in subjects with MCD are reported, suggesting that microtubule-dependent mitotic and postmitotic processes are major contributors to the pathogenesis of MCD.
Journal ArticleDOI
Tubulin tyrosination is a major factor affecting the recruitment of CAP-Gly proteins at microtubule plus ends
Leticia Peris,Manuel Théry,Julien Fauré,Yasmina Saoudi,Laurence Lafanechère,John K. Chilton,Phillip R. Gordon-Weeks,Niels Galjart,Michel Bornens,Linda Wordeman,Juergen Wehland,Annie Andrieux,Didier Job +12 more
TL;DR: It is shown that in mammalian fibroblasts, cytoplasmic linker protein (CLIP) 170 and other microtubule plus-end tracking proteins comprising a cytoskeleton-associated protein glycine-rich (CAP-Gly) micro Tubule binding domain such as CLIP-115 and p150 Glued, localize to the ends of tyrosinated microtubules but not to the Ends of detyrosinatedmicrotubules.
Journal ArticleDOI
Motor-dependent microtubule disassembly driven by tubulin tyrosination
Leticia Peris,Michael Wagenbach,Laurence Lafanechère,Laurence Lafanechère,Laurence Lafanechère,Jacques Brocard,Jacques Brocard,Jacques Brocard,Ayana T. Moore,Frank Kozielski,Didier Job,Didier Job,Didier Job,Linda Wordeman,Annie Andrieux,Annie Andrieux,Annie Andrieux +16 more
TL;DR: Detyrosination of transiently stabilized MTs may give rise to persistent subpopulations of disassembly-resistant polymers to sustain subcellular cytoskeletal differentiation.