A
Arnon Nagler
Researcher at Sheba Medical Center
Publications - 1435
Citations - 51740
Arnon Nagler is an academic researcher from Sheba Medical Center. The author has contributed to research in topics: Transplantation & Hematopoietic stem cell transplantation. The author has an hindex of 98, co-authored 1316 publications receiving 44298 citations. Previous affiliations of Arnon Nagler include French Institute of Health and Medical Research & University of Paris.
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Journal ArticleDOI
Upregulation of Senescent/Exhausted Phenotype of CAR T Cells and Induction of Both Treg and Myeloid Suppressive Cells Correlate with Reduced Response to CAR T Cell Therapy in Relapsed/Refractory B Cell Malignancies
Katia Beider,Michal J. Besser,Jacob Schachter,Ania Hava Grushchenko-Polaq,Valeria Voevoda,Idit Wolf,Olga Ostrovsky,Elad Jacoby,Avichai Shimoni,Arnon Nagler +9 more
TL;DR: The frequency and kinetics of regulatory T cells and myeloid suppressor cells in the peripheral blood of the CAR T treated pts and the immunoregulatory and senescent/exhausted phenotype in CAR T products were evaluated.
Journal ArticleDOI
Prevention and treatment of relapse after stem cell transplantation with immunotherapy.
Nicola Gökbuget,Jonathan Canaani,Arnon Nagler,Michael R. Bishop,Nicolaus Kröger,David Avigan +5 more
TL;DR: Presentations on checkpoint inhibitors, vaccination strategies, and novel antibody therapies, which were presented and discussed at the third International Workshop on Biology, Prevention, and Treatment of Relapse after Stem Cell Transplantation are summarized.
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Repetitively Administered Low-Dose Donor Lymphocyte Infusion for Prevention of Relapse after Allogeneic Stem Cell Transplantation in Patients with High-Risk Acute Leukemia.
Panagiotis Tsirigotis,Konstantinos Gkirkas,Vassiliki Kitsiou,Spiros Chondropoulos,Theofilos Athanassiades,Thomas P. Thomopoulos,Alexandra Tsirogianni,Maria Stamouli,Aggeliki Karagiannidi,Nikolaos Siafakas,Vassiliki Pappa,Arnon Nagler +11 more
TL;DR: In this article, the authors tested the safety and efficacy of a novel method of prophylactic donor lymphocyte infusion (pro-DLI) based by repetitive administration of low lymphocyte doses.
Journal ArticleDOI
Outcomes of Advanced Hodgkin Lymphoma after Umbilical Cord Blood Transplantation: A Eurocord and EBMT Lymphoma and Cellular Therapy & Immunobiology Working Party Study.
Annalisa Paviglianiti,Karina Tozatto Maio,Vanderson Rocha,Eve Gehlkopf,Noel Milpied,Albert Esquirol,Patrice Chevallier,Didier Blaise,Anne Claire Gac,Véronique Leblond,Jean-Yves Cahn,Manuel Abecasis,Tsila Zuckerman,Harry C. Schouten,Gunhan Gurman,Marie-Thérèse Rubio,Yves Beguin,Lucía López Corral,Arnon Nagler,John A. Snowden,Yener Koc,Nicola Mordini,Francesca Bonifazi,Fernanda Volt,Chantal Kenzey,Stephen P. Robinson,Silvia Montoto,Eliane Gluckman,Annalisa Ruggeri +28 more
TL;DR: UCBT is feasible in heavily pretreated patients with HL, and the reduced-intensity conditioning regimen with Cy+Flu+2GyTBI is associated with a better OS and NRM, however, outcomes are poor in patients not in CR at UCBT.
Journal Article
Total lymphoid irradiation, anti-lymphocyte globulin and Campath 1-G for immunosuppression prior to bone marrow transplantation for aplastic anomia after repeated graft rejection
R. Or,Jayesh Mehta,Joseph Kapelushnik,M. Aker,Naparstek E,Arnon Nagler,G. Cividalli,S. Slavin +7 more
TL;DR: A child with aplastic anemia who rejected donor marrow twice despite adequate immunosuppression as part of the conditioning therapy but engrafted successfully following combined administration of three modalities of immunos Puppression.