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Arnon Nagler
Researcher at Sheba Medical Center
Publications - 1435
Citations - 51740
Arnon Nagler is an academic researcher from Sheba Medical Center. The author has contributed to research in topics: Transplantation & Hematopoietic stem cell transplantation. The author has an hindex of 98, co-authored 1316 publications receiving 44298 citations. Previous affiliations of Arnon Nagler include French Institute of Health and Medical Research & University of Paris.
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Journal ArticleDOI
Multiple myeloma cells recruit tumor-supportive macrophages through the CXCR4/CXCL12 axis and promote their polarization toward the M2 phenotype
Katia Beider,Hanna Bitner,Merav Leiba,Odit Gutwein,Maya Koren-Michowitz,Olga Ostrovsky,Michal Abraham,Hanna Wald,Eithan Galun,Amnon Peled,Arnon Nagler +10 more
TL;DR: Results identify macrophages as important players in MM tumorogenicity, and recognize the CXCR4/CXCL12 axis as a critical regulator of MM-stroma interactions and microenvironment formation.
Journal ArticleDOI
Outcomes of allogeneic haematopoietic stem cell transplantation from HLA-matched and alternative donors: a European Society for Blood and Marrow Transplantation registry retrospective analysis.
Roni Shouval,Joshua A Fein,Myriam Labopin,Nicolaus Kröger,Rafael F. Duarte,Peter Bader,Christian Chabannon,Jürgen Kuball,Grzegorz W. Basak,Carlo Dufour,Jacques-Emmanuel Galimard,Emmanuelle Polge,Arjan C. Lankester,Silvia Montoto,John A. Snowden,Jan Styczyński,Ibrahim Yakoub-Agha,Mohamad Mohty,Arnon Nagler +18 more
TL;DR: Overall survival following allogeneic stem cell transplantation is improving with substantial progress among recipients of haploidentical and cord blood HSCT, and the traditional donor hierarchy of matched sibling donors followed by matched unrelated donors and then other donors holds.
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Transplantation of human bone marrow mesenchymal stem cells as a thin subretinal layer ameliorates retinal degeneration in a rat model of retinal dystrophy
Adi Tzameret,Ifat Sher,Michael Belkin,Avraham J. Treves,Amilia Meir,Arnon Nagler,Hani Levkovitch-Verbin,Iris Barshack,Mordechai Rosner,Ygal Rotenstreich +9 more
TL;DR: It is suggested that transplantation of hBM-MSCs as a thin subretinal layer enhances the therapeutic effect and the safety of cell transplantation.
Journal ArticleDOI
Expression profiles of acute lymphoblastic and myeloblastic leukemias with ALL-1 rearrangements
T Rozovskaia,O. Ravid-Amir,Sergei Tillib,Godfrey S. Getz,E. Feinstein,Hari Om Agrawal,Arnon Nagler,Eric F. Rappaport,Irina Issaeva,Y. Matsuo,U. R. Kees,Tsvee Lapidot,F Lo Coco,Robert Foa,Alexander Mazo,Tomonori Nakamura,Carlo M. Croce,Giuseppe Cimino,Eytan Domany,Eli Canaani +19 more
TL;DR: The extensive analysis described here pinpointed genes that might have a direct role in pathogenesis, including 43 genes that exhibited expression profiles closely linked to ALLs with ALL-1 rearrangements.
Journal ArticleDOI
The effect of prior exposure to imatinib on transplant-related mortality
Michael W. Deininger,Michael Schleuning,Hilde Greinix,Herbert G. Sayer,Thomas Fischer,Jesus Martinez,Richard T. Maziarz,Eduardo Olavarria,Leo F. Verdonck,Kerstin Schaefer,Conxa Boqué,Edgar Faber,Arnon Nagler,Enrico Pogliani,Nigel H. Russell,Liisa Volin,Urs Schanz,Gottfried Doelken,Michael G. Kiehl,Axel A. Fauser,Brian J. Druker,Anna Sureda,Simona Iacobelli,Ronald Brand,Rainer Krahl,Thoralf Lange,Andreas Hochhaus,Alois Gratwohl,Hans J. Kolb,Dietger Niederwieser +29 more
TL;DR: In this paper, the authors used multivariate analysis to define factors associated with major outcomes (engraftment, graft-versus-host disease, relapse, non-relapse mortality) in addition to descriptive statistics.