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Barry Iacopetta
Researcher at University of Western Australia
Publications - 190
Citations - 14545
Barry Iacopetta is an academic researcher from University of Western Australia. The author has contributed to research in topics: Colorectal cancer & Microsatellite instability. The author has an hindex of 64, co-authored 190 publications receiving 13770 citations. Previous affiliations of Barry Iacopetta include University of Palermo & Council on Education for Public Health.
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Journal ArticleDOI
Tumor-Infiltrating FOXP3+ T Regulatory Cells Show Strong Prognostic Significance in Colorectal Cancer
Paul Salama,Michael Phillips,Fabienne Grieu,Melinda Morris,Nik Zeps,David Joseph,Cameron Platell,Barry Iacopetta +7 more
TL;DR: The inclusion of FOXP3(+) Treg density in normal and tumor tissue had stronger prognostic significance in colorectal cancer compared with CD8(+) and CD45RO(+) lymphocytes, and may help to improve the prognostication of early-stage coloreCTal cancer.
Journal ArticleDOI
Kirsten ras mutations in patients with colorectal cancer: the ‘RASCAL II’ study
H J N Andreyev,A. R. Norman,David Cunningham,Jacqui Oates,B. R. Dix,Barry Iacopetta,J. Young,T. Walsh,Robyn L. Ward,Nicholas J. Hawkins,M. Beranek,P. Jandik,Robert Benamouzig,E. Jullian,Pierre Laurent-Puig,Sylviane Olschwang,Oliver Müller,Ingrid Hoffmann,H. M. Rabes,C. Zietz,C. Troungos,C. Valavanis,S T Yuen,Jwc Ho,C. T. Croke,D. P. O'Donoghue,Walter Giaretti,A. Rapallo,Antonio Russo,Viviana Bazan,M. Tanaka,K. Omura,T. Azuma,Toshifumi Ohkusa,Takahiro Fujimori,Y. Ono,M. Pauly,C. Faber,R. Glaesener,A.F.P.M. de Goeij,Jan-Willem Arends,S. N. Andersen,T. Lovig,J. Breivik,Gustav Gaudernack,Ole Petter F. Clausen,P.M. De Angelis,G. I. Meling,T. O. Rognum,R. Smith,H S Goh,A. Font,Rafael Rosell,Xiao-Feng Sun,Hong Zhang,J. Benhattar,L. Losi,Jenq Chang Lee,Shan Tair Wang,Paul A. Clarke,Sandra M. Bell,Philip Quirke,Vivien J. Bubb,J. Piris,N. R. Cruickshank,Dion Morton,J. C. Fox,Fahd Al-Mulla,N. Lees,C. N. Hall,D. Snary,K. Wilkinson,Deborah A. Dillon,Jose Costa,V. E. Pricolo,S. D. Finkelstein,J. S. Thebo,Anthony J. Senagore,S. A. Halter,S. Wadler,S Malik,K. Krtolica,N. Urosevic +82 more
TL;DR: In this paper, the effect of the Kirsten ras (Ki-ras) tumour genotype and outcome of patients with colorectal cancer was investigated using a multivariate analysis.
Journal ArticleDOI
Are there two sides to colorectal cancer
TL;DR: Differences between normal right and left colonic segments that could favour progression through different tumourigenic pathways are summarized in this review and the existence of 2 broadly different groups of cancer defined by site of origin in the colon should be considered.
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Evaluation of tumor microsatellite instability using five quasimonomorphic mononucleotide repeats and pentaplex PCR.
Nirosha Suraweera,Alex Duval,Maryline Reperant,Christelle Vaury,Daniela Furlan,Karen Leroy,Raquel Seruca,Barry Iacopetta,Richard Hamelin +8 more
TL;DR: It is proposed that using a pentaplex polymerase chain reaction system allows accurate evaluation of tumor MSI status of DNA with 100% sensitivity and specificity without the need to match normal DNA.
Journal ArticleDOI
Association of tumour site and sex with survival benefit from adjuvant chemotherapy in colorectal cancer
TL;DR: The survival benefits seen in patients treated with adjuvant chemotherapy suggest that data from previous trials of adjUvant chemotherapy should be reassessed and the predictive value of MSI status confirmed.