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Behnam Nabet
Researcher at Harvard University
Publications - 67
Citations - 5510
Behnam Nabet is an academic researcher from Harvard University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 23, co-authored 51 publications receiving 3961 citations. Previous affiliations of Behnam Nabet include Northwestern University & Fred Hutchinson Cancer Research Center.
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Journal ArticleDOI
A compendium of RNA-binding motifs for decoding gene regulation
Debashish Ray,Hilal Kazan,Kate B. Cook,Matthew T. Weirauch,Matthew T. Weirauch,Hamed S. Najafabadi,Xiao Li,Serge Gueroussov,Mihai Albu,Hong Zheng,Ally Yang,Hong Na,Manuel Irimia,Leah H. Matzat,Ryan K. Dale,Sarah A. Smith,Christopher A. Yarosh,Seth M. Kelly,Behnam Nabet,D. Mecenas,Weimin Li,Rakesh S. Laishram,Mei Qiao,Howard D. Lipshitz,Fabio Piano,Anita H. Corbett,Russ P. Carstens,Brendan J. Frey,Richard A. Anderson,Kristen W. Lynch,Luiz O. F. Penalva,Elissa P. Lei,Andrew G. Fraser,Benjamin J. Blencowe,Quaid Morris,Timothy P. Hughes +35 more
TL;DR: A systematic analysis of the RNA motifs recognized by RNA-binding proteins, encompassing 205 distinct genes from 24 diverse eukaryotes, provides an unprecedented overview of RNA- binding proteins and their targets, and constitute an invaluable resource for determining post-transcriptional regulatory mechanisms in eukARYotes.
Journal ArticleDOI
YY1 Is a Structural Regulator of Enhancer-Promoter Loops
Abraham S. Weintraub,Charles H. Li,Alicia V. Zamudio,Alla A. Sigova,Nancy M. Hannett,Daniel S. Day,Brian J. Abraham,Malkiel A. Cohen,Behnam Nabet,Dennis L. Buckley,Yang Eric Guo,Denes Hnisz,Rudolf Jaenisch,James E. Bradner,Nathanael S. Gray,Richard A. Young +15 more
TL;DR: It is shown that the ubiquitously expressed transcription factor Yin Yang 1 (YY1) contributes to enhancer-promoter structural interactions in a manner analogous to DNA interactions mediated by CTCF.
Journal ArticleDOI
ESRP1 and ESRP2 Are Epithelial Cell-Type-Specific Regulators of FGFR2 Splicing
TL;DR: Empithelial Splicing Regulatory Proteins 1 and 2 (ESRP1 and ESRP2) are coordinators of an epithelial cell-type-specific splicing program that regulates splicing during the epithelial-to-mesenchymal transition (EMT).
Journal ArticleDOI
The dTAG system for immediate and target-specific protein degradation
Behnam Nabet,Justin M. Roberts,Dennis L. Buckley,Dennis L. Buckley,Joshiawa Paulk,Joshiawa Paulk,Shiva Dastjerdi,Annan Yang,Alan L. Leggett,Michael A. Erb,Matthew A. Lawlor,Amanda Souza,Amanda Souza,Thomas G. Scott,Sarah Vittori,Jennifer A. Perry,Jun Qi,Georg E. Winter,Georg E. Winter,Kwok-Kin Wong,Nathanael S. Gray,James E. Bradner,James E. Bradner +22 more
TL;DR: The dTAG system pairs potent heterobifunctional degraders and extensible tagging strategies to achieve immediate and reversible degradation of divergent proteins, facilitating biological investigation and drug target validation in cells and in mice.
YY1 Is a Structural Regulator of Enhancer-Promoter Loops
Alla A. Sigova,Nancy M. Hannett,Daniel S. Day,Brian J. Abraham,Malkiel A. Cohen,Behnam Nabet,Dennis L. Buckley,Yang Eric Guo,Denes Hnisz,James E. Bradner,Nathanael S. Gray,Abraham S. Weintraub,Charles H. Li,Alicia Zamudio Montes de Oca,Rudolf Jaenisch,Richard A. Young +15 more
TL;DR: In this paper, the ubiquitously expressed transcription factor Yin Yang 1 (YY1) contributes to enhancer-promoter structural interactions in a manner analogous to DNA interactions mediated by CTCF.