C
Carol A. Tamminga
Researcher at University of Texas Southwestern Medical Center
Publications - 668
Citations - 36656
Carol A. Tamminga is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: Psychosis & Schizophrenia. The author has an hindex of 90, co-authored 636 publications receiving 32680 citations. Previous affiliations of Carol A. Tamminga include Johns Hopkins University & Long Island Jewish Medical Center.
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Journal ArticleDOI
Molecular Adaptations Underlying Susceptibility and Resistance to Social Defeat in Brain Reward Regions
Vaishnav Krishnan,Ming-Hu Han,Danielle Graham,Olivier Berton,William Renthal,Scott J. Russo,Quincey LaPlant,Ami Graham,Michael Lutter,Diane C. Lagace,Subroto Ghose,Robin Reister,Paul Tannous,Thomas A. Green,Rachael L. Neve,Sumana Chakravarty,Arvind Kumar,Amelia J. Eisch,David W. Self,Francis S. Lee,Carol A. Tamminga,Donald C. Cooper,Howard K. Gershenfeld,Eric J. Nestler +23 more
TL;DR: It is shown that molecular recapitulations of three prototypical adaptations associated with the unsusceptible phenotype are each sufficient to promote resistant behavior and validate a multidisciplinary approach to examine the neurobiological mechanisms of variations in stress resistance.
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Positron emission tomography reveals elevated D2 dopamine receptors in drug-naive schizophrenics
Dean F. Wong,Henry N. Wagner,Larry E. Tune,Robert F. Dannals,Godfrey D. Pearlson,Jonathan M. Links,Carol A. Tamminga,Emmanuel P. Broussolle,Emmanuel P. Broussolle,Hayden T. Ravert,Alan A. Wilson,J. K. Thomas Toung,Jan Malat,Jeffery A. Williams,Lorcan A. O'Tuama,Solomon H. Snyder,Michael J. Kuhar,Michael J. Kuhar,Albert Gjedde,Albert Gjedde +19 more
TL;DR: Schizophrenia itself is associated with an increase in brain D2 dopamine receptor density, and the densities in the caudate nucleus were higher in both groups of patients than in the normal volunteers.
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Subanesthetic doses of ketamine stimulate psychosis in schizophrenia
TL;DR: Ketamine-induced psychotic symptoms were strikingly reminiscent of the subject's symptoms during active episodes of their illness, and antagonism of NMDA-sensitive glutamatergic transmission in brain exacerbates symptoms of schizophrenia.
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Altered Gene Expression of Brain-Derived Neurotrophic Factor and Receptor Tyrosine Kinase B in Postmortem Brain of Suicide Subjects
Yogesh Dwivedi,Hooriyah S. Rizavi,Robert R. Conley,Rosalinda C. Roberts,Carol A. Tamminga,Ghanshyam N. Pandey +5 more
TL;DR: Findings of reduced expression of BDNF and trk B in postmortem brain in suicide subjects suggest that these molecules may play an important role in the pathophysiological aspects of suicidal behavior.
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Effects of Ketamine in Normal and Schizophrenic Volunteers
TL;DR: NVs could be used for many informative experimental psychosis studies involving ketamine interviews and the data suggest that the phencyclidine (PCP) model of schizophrenia maybe a more valid human psychosis/schizophrenia drug model than the amphetamine model, with a broader range of psychotic symptoms.