C
Catherine Lavazec
Researcher at Paris Descartes University
Publications - 34
Citations - 1555
Catherine Lavazec is an academic researcher from Paris Descartes University. The author has contributed to research in topics: Plasmodium falciparum & Gametocyte. The author has an hindex of 20, co-authored 28 publications receiving 1383 citations. Previous affiliations of Catherine Lavazec include Centre national de la recherche scientifique & Pasteur Institute.
Papers
More filters
Journal ArticleDOI
Expression switching in the stevor and Pfmc-2TM superfamilies in Plasmodium falciparum
TL;DR: Evidence is provided that the stevor and Pfmc‐2TM gene families play a role in P. falciparum antigenic variation, and chromosomal telomeric deletions are common in clonal lines and result in a spectrum of deletion genotypes.
Journal ArticleDOI
A switch in infected erythrocyte deformability at the maturation and blood circulation of Plasmodium falciparum transmission stages
Marta Tibúrcio,Makhtar Niang,Guillaume Deplaine,Sylvie Perrot,Emmanuel Bischoff,Papa Alioune Ndour,Francesco Silvestrini,Ayman Khattab,Geneviève Milon,Peter H. David,Max R. Hardeman,Kenneth D. Vernick,Robert W. Sauerwein,Peter R. Preiser,Odile Mercereau-Puijalon,Pierre Buffet,Pietro Alano,Catherine Lavazec,Catherine Lavazec +18 more
TL;DR: It is shown that mature GIEs are more deformable than immature stages using ektacytometry and microsphiltration methods, and that a switch in cellular deformability in the transition from immature to mature gametocytes is accompanied by the deassociation of parasite-derived STEVOR proteins from the infected erythrocyte membrane.
Journal ArticleDOI
The Plasmodium TRAP/MIC2 family member, TRAP‐Like Protein (TLP), is involved in tissue traversal by sporozoites
Cristina K. Moreira,Thomas J. Templeton,Catherine Lavazec,Rhian E. Hayward,Charlotte V. Hobbs,Hans Kroeze,Chris J. Janse,Andrew P. Waters,Photini Sinnis,Alida Coppi +9 more
TL;DR: A new member of the TRAP/MIC2 family, named TRAP‐Like Protein (TLP), that is highly conserved within the Plasmodium genus is characterized, indicating a role of TLP in cell traversal by sporozoites.
Journal ArticleDOI
Hypervariability within the Rifin, Stevor and Pfmc-2TM superfamilies in Plasmodium falciparum
TL;DR: Evidence is presented that the Stevor and Pfmc-2TM families are exported to the erythrocyte membrane, thus supporting the hypothesis that host immune pressure drives antigenic diversity within the loop, and an examination of multiple P.falciparum isolates demonstrates that the hypervariable loop within Stevor et al. possesses sequence diversity across isolate boundaries.
Journal ArticleDOI
Carboxypeptidases B of Anopheles gambiae as targets for a Plasmodium falciparum transmission-blocking vaccine.
Catherine Lavazec,Christian Boudin,Renaud Lacroix,Sarah Bonnet,A. Diop,Sabine Thiberge,Bertrand Boisson,Rachida Tahar,Catherine Bourgouin +8 more
TL;DR: Results indicate that A. gambiae CPBs could constitute targets for a TBV that is based upon mosquito molecules that could likely contribute to reducing Plasmodium transmission.