C
Catherine Lavazec
Researcher at Paris Descartes University
Publications - 34
Citations - 1555
Catherine Lavazec is an academic researcher from Paris Descartes University. The author has contributed to research in topics: Plasmodium falciparum & Gametocyte. The author has an hindex of 20, co-authored 28 publications receiving 1383 citations. Previous affiliations of Catherine Lavazec include Centre national de la recherche scientifique & Pasteur Institute.
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Journal ArticleDOI
Mosquito-based transmission blocking vaccines for interrupting Plasmodium development.
TL;DR: Recent advances in the identification of promising candidate antigens for a mosquito-based transmission blocking vaccine are reviewed.
Journal ArticleDOI
Plasmodium Merozoite TRAP Family Protein Is Essential for Vacuole Membrane Disruption and Gamete Egress from Erythrocytes.
Daniel Y. Bargieri,Daniel Y. Bargieri,Sabine Thiberge,Chwen L. Tay,Alison F. Carey,Alison F. Carey,Alice Rantz,Florian Hischen,Audrey Lorthiois,Ursula Straschil,Pallavi Singh,Shailja Singh,Tony Triglia,Takafumi Tsuboi,Alan F. Cowman,Alan F. Cowman,Chetan E. Chitnis,Pietro Alano,Jake Baum,Gabriele Pradel,Catherine Lavazec,Robert Ménard +21 more
TL;DR: Surface-associated TRAP (thrombospondin-related anonymous protein) family proteins are conserved across the phylum of apicomplexan parasites, indicating that motor-binding TRAP family members function not just in parasite motility and cell invasion but also in membrane disruption and cell egress.
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Plasmodium falciparum STEVOR phosphorylation regulates host erythrocyte deformability enabling malaria parasite transmission
Bernina Naissant,Florian Dupuy,Yoann Duffier,Audrey Lorthiois,Julien Duez,Judith A. M. Scholz,Pierre Buffet,Anais Merckx,Anais Merckx,Anna Bachmann,Catherine Lavazec +10 more
TL;DR: Evidence is produced that the increase of GIE stiffness induced by sildenafil (Viagra) is dependent on STEVOR phosphorylation status and on another independent mechanism, and new insights are provided into mechanisms by which phosphodiesterase inhibitors may block malaria parasite transmission.
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Analysis of mutant Plasmodium berghei parasites lacking expression of multiple PbCCp genes.
Catherine Lavazec,Cristina K. Moreira,Gunnar R. Mair,Andrew P. Waters,Chris J. Janse,Thomas J. Templeton +5 more
TL;DR: Transcript expression analysis by quantitative real time RT-PCR showed that as in the human malaria parasite, Plasmodium falciparum, all PbCCp genes are predominantly transcribed in the gametocyte stage with a low level of transcription in the oocyst stage.
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Erythrocyte remodeling by Plasmodium falciparum gametocytes in the human host interplay
TL;DR: Recent studies of the molecular and cellular remodeling of the host erythrocyte induced by P. falciparum during gametocyte maturation are shedding light on how these may affect the establishment and maintenance of sequestration of the immature transmission stages and the subsequent release and circulation of mature gametocytes in the peripheral bloodstream.