Catherine Lavazec

TL;DR: Evidence is provided that the stevor and Pfmc‐2TM gene families play a role in P. falciparum antigenic variation, and chromosomal telomeric deletions are common in clonal lines and result in a spectrum of deletion genotypes.

TL;DR: It is shown that mature GIEs are more deformable than immature stages using ektacytometry and microsphiltration methods, and that a switch in cellular deformability in the transition from immature to mature gametocytes is accompanied by the deassociation of parasite-derived STEVOR proteins from the infected erythrocyte membrane.

TL;DR: A new member of the TRAP/MIC2 family, named TRAP‐Like Protein (TLP), that is highly conserved within the Plasmodium genus is characterized, indicating a role of TLP in cell traversal by sporozoites.

TL;DR: Evidence is presented that the Stevor and Pfmc-2TM families are exported to the erythrocyte membrane, thus supporting the hypothesis that host immune pressure drives antigenic diversity within the loop, and an examination of multiple P.falciparum isolates demonstrates that the hypervariable loop within Stevor et al. possesses sequence diversity across isolate boundaries.

TL;DR: Results indicate that A. gambiae CPBs could constitute targets for a TBV that is based upon mosquito molecules that could likely contribute to reducing Plasmodium transmission.