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Changquan Calvin Sun
Researcher at University of Minnesota
Publications - 248
Citations - 10301
Changquan Calvin Sun is an academic researcher from University of Minnesota. The author has contributed to research in topics: Tableting & Cocrystal. The author has an hindex of 45, co-authored 223 publications receiving 8070 citations. Previous affiliations of Changquan Calvin Sun include Pharmacia & Pfizer.
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Polymorphs, Salts, and Cocrystals: What’s in a Name?
Srinivasulu Aitipamula,Rahul Banerjee,Arvind K. Bansal,Kumar Biradha,Miranda L. Cheney,Angshuman Roy Choudhury,Gautam R. Desiraju,Amol G. Dikundwar,Ritesh Dubey,Naga Kiran Duggirala,Preetam P. Ghogale,Soumyajit Ghosh,Pramod Kumar Goswami,N. Rajesh Goud,Ram K. R. Jetti,Piotr H. Karpinski,Poonam Kaushik,Dinesh Kumar,Vineet Kumar,Brian Moulton,Arijit Mukherjee,Gargi Mukherjee,Allan S. Myerson,Vibha Puri,Arunachalam Ramanan,T. Rajamannar,C. Malla Reddy,Naír Rodríguez-Hornedo,Robin D. Rogers,T. N. Guru Row,Palash Sanphui,Ning Shan,Ganesh Shete,Amit Singh,Changquan Calvin Sun,Jennifer A. Swift,Ram Thaimattam,Tejender S. Thakur,Rajesh Kumar Thaper,Sajesh P. Thomas,Srinu Tothadi,Venu R. Vangala,Narayan Variankaval,Peddy Vishweshwar,David R. Weyna,Michael J. Zaworotko +45 more
TL;DR: A discussion of the FDA guidance on regulatory classification of pharmaceutical cocrystals of active pharmaceutical ingredients (APIs) was held in Manesar near Delhi, India, from February 2-4, 2012 as mentioned in this paper.
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Characterization of thermal behavior of deep eutectic solvents and their potential as drug solubilization vehicles.
TL;DR: Deep eutectic solvent can be a promising vehicle for increasing exposure of poorly soluble compounds in preclinical studies and in solubility in DES is 5 to 22,000 folds more than that in water.
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Evaluation of the effects of tableting speed on the relationships between compaction pressure, tablet tensile strength, and tablet solid fraction.
TL;DR: It is proposed that the compactibility profile (tensile strength vs. solid fraction) is a predictor that is independent of tableting speed and can be used to predict tablet strength during formulation development and scale up.
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Improving Mechanical Properties of Caffeine and Methyl Gallate Crystals by Cocrystallization
Changquan Calvin Sun,Hao Hou +1 more
TL;DR: In this article, a 1:1 cocrystal of caffeine and methyl gallate was formed by suspending powders of the two pure compounds in ethanol, and the tabletability of the cocrestal was excellent over the entire pressure range.
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Influence of crystal structure on the tableting properties of sulfamerazine polymorphs.
TL;DR: To understand the influence of polymorphic structure on the tableting properties of sulfamerazine, molecular simulation reveals slip planes in crystals of I but not in II, which confer greater plasticity to crystals of II than II and therefore greater tabletability.