C
Chris A. Whitehouse
Researcher at United States Army Medical Research Institute of Infectious Diseases
Publications - 72
Citations - 5793
Chris A. Whitehouse is an academic researcher from United States Army Medical Research Institute of Infectious Diseases. The author has contributed to research in topics: Virus & Monkeypox virus. The author has an hindex of 31, co-authored 64 publications receiving 4608 citations. Previous affiliations of Chris A. Whitehouse include University of Kentucky & United States Geological Survey.
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Journal ArticleDOI
Crimean–Congo hemorrhagic fever
TL;DR: The history, epidemiology, ecology, clinical features, pathogenesis, diagnosis, and treatment of CCHF are reviewed, and issues related to its possible use as a bioterrorism agent are discussed.
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Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in Klebsiella pneumoniae, an urgent threat to public health
Kathryn E. Holt,Heiman F. L. Wertheim,Ruth N. Zadoks,Stephen Baker,Chris A. Whitehouse,David A. B. Dance,Adam Jenney,Thomas R. Connor,Li Yang Hsu,Juliëtte A. Severin,Sylvain Brisse,Hanwei Cao,Jonathan J. Wilksch,Claire L. Gorrie,Mark B. Schultz,David J. Edwards,Kinh Van Nguyen,Trung Vu Nguyen,Trinh Tuyet Dao,Martijn Mensink,Vien Le Minh,Nguyen Thi Khanh Nhu,Constance Schultsz,Kuntaman Kuntaman,Paul N. Newton,Paul N. Newton,Catrin E. Moore,Catrin E. Moore,Richard A. Strugnell,Nicholas R. Thomson,Nicholas R. Thomson +30 more
TL;DR: The DNA sequence of K. pneumoniae isolates from around the world is determined and it is shown that there is a wide spectrum of diversity, including variation within shared sequences and gain and loss of whole genes, and there is an unrecognized association between the possession of specific gene profiles associated with virulence and antibiotic resistance.
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Crimean-Congo hemorrhagic fever: history, epidemiology, pathogenesis, clinical syndrome and genetic diversity.
Dennis A. Bente,Naomi L. Forrester,Douglas M. Watts,Alexander J. McAuley,Chris A. Whitehouse,Mike Bray +5 more
TL;DR: Current knowledge of CCHFV is summarized, summarizing its molecular biology, maintenance and transmission, epidemiology and geographic range, including an extensive discussion of C CHFV genetic diversity, including maps of the range of the virus with superimposed phylogenetic trees.
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Smallpox vaccine–induced antibodies are necessary and sufficient for protection against monkeypox virus
Yvette Edghill-Smith,Hana Golding,Jody Manischewitz,Lisa R. King,Dorothy E. Scott,Mike Bray,Aysegul Nalca,Jay W. Hooper,Chris A. Whitehouse,Joern E. Schmitz,Keith A. Reimann,Genoveffa Franchini +11 more
TL;DR: It is reported that vaccinia-specific B-cell responses are essential for protection of macaques from monkeypox virus, a variola virus ortholog, and vaccines able to induce long-lasting protective antibody responses may constitute realistic alternatives to the currently available smallpox vaccine.
Journal ArticleDOI
Campylobacter jejuni Cytolethal Distending Toxin Causes a G2-Phase Cell Cycle Block
Chris A. Whitehouse,Paul B. Balbo,Everett C. Pesci,D L Cottle,Peter M. Mirabito,Carol L. Pickett +5 more
TL;DR: Results indicated that CDT treatment results in a failure to activate CDC2, which leads to cell cycle arrest in G2, and provides a model for the generation of diarrheal disease by C. jejuni and other diarrheagenic bacteria that produce CDT.