C
Christian Larroque
Researcher at University of Montpellier
Publications - 114
Citations - 3782
Christian Larroque is an academic researcher from University of Montpellier. The author has contributed to research in topics: Cytochrome & Essential oil. The author has an hindex of 29, co-authored 107 publications receiving 3371 citations. Previous affiliations of Christian Larroque include Centre national de la recherche scientifique & Universidad Técnica Particular de Loja.
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Journal ArticleDOI
Cellular localisation of a water-soluble fullerene derivative
Sarah Foley,Colin Crowley,Monique Smaïhi,Claude Bonfils,Bernard F. Erlanger,Patrick Seta,Christian Larroque +6 more
TL;DR: It is demonstrated that a fullerene derivative could cross the external cellular membrane and it localises preferentially to the mitochondria, and it is proposed that this finding supports the potential use of fullerenes as drug delivery agents as their structure mimics that of clathrin known to mediate endocytosis.
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A Family of Protein-Deglutamylating Enzymes Associated with Neurodegeneration
Krzysztof Rogowski,Juliette van Dijk,Maria M. Magiera,Christophe Bosc,Jean-Christophe Deloulme,Anouk Bosson,Leticia Peris,Nicholas D. Gold,Benjamin Lacroix,Montserrat Bosch Grau,Nicole Bec,Christian Larroque,Solange Desagher,Max Holzer,Annie Andrieux,Marie-Jo Moutin,Carsten Janke +16 more
TL;DR: The results reveal that controlling the length of the polyglutamate side chains on tubulin is critical for neuronal survival and is directly linked to neurodegeneration.
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FANCD2 Binds MCM Proteins and Controls Replisome Function upon Activation of S Phase Checkpoint Signaling
Gérald Lossaint,Marion Larroque,Cyril Ribeyre,Nicole Bec,Christian Larroque,Chantal Décaillet,Kerstin Gari,Angelos Constantinou +7 more
TL;DR: It is found that FANCD2 can interact directly with minichromosome maintenance (MCM) proteins and is an effector of ATR signaling implicated in a general replisome surveillance mechanism that is necessary for sustaining cell proliferation and attenuating carcinogenesis.
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The TOGp protein is a new human microtubule-associated protein homologous to the Xenopus XMAP215
S. Charrasse,M. Schroeder,C. Gauthier-Rouviere,Fabrice Ango,Lynne Cassimeris,D.L. Gard,Christian Larroque +6 more
TL;DR: In this article, the authors identified a 6,449 bp cDNA, termed colonic, hepatic tumor over-expressed gene (ch-TOG), that is highly expressed in human tumors and brain.
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Inhibition of CD39 Enzymatic Function at the Surface of Tumor Cells Alleviates Their Immunosuppressive Activity
Jérémy Bastid,Anne Regairaz,Nathalie Bonnefoy,Cécile Dejou,Jérôme Giustiniani,Caroline Laheurte,Stéphanie Cochaud,Emilie Laprevotte,Elisa Funck-Brentano,Patrice Hemon,Laurent Gros,Nicole Bec,Christian Larroque,Gilles Alberici,Armand Bensussan,Jean-François Eliaou +15 more
TL;DR: Interference with the CD39–adenosine pathway may represent a novel immunotherapeutic strategy for inhibiting tumor cell–mediated immunosuppression.