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Nicole Bec
Researcher at University of Montpellier
Publications - 74
Citations - 2430
Nicole Bec is an academic researcher from University of Montpellier. The author has contributed to research in topics: Essential oil & Hydrostatic pressure. The author has an hindex of 24, co-authored 68 publications receiving 2085 citations. Previous affiliations of Nicole Bec include Centre national de la recherche scientifique & French Institute of Health and Medical Research.
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Journal ArticleDOI
A Family of Protein-Deglutamylating Enzymes Associated with Neurodegeneration
Krzysztof Rogowski,Juliette van Dijk,Maria M. Magiera,Christophe Bosc,Jean-Christophe Deloulme,Anouk Bosson,Leticia Peris,Nicholas D. Gold,Benjamin Lacroix,Montserrat Bosch Grau,Nicole Bec,Christian Larroque,Solange Desagher,Max Holzer,Annie Andrieux,Marie-Jo Moutin,Carsten Janke +16 more
TL;DR: The results reveal that controlling the length of the polyglutamate side chains on tubulin is critical for neuronal survival and is directly linked to neurodegeneration.
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FANCD2 Binds MCM Proteins and Controls Replisome Function upon Activation of S Phase Checkpoint Signaling
Gérald Lossaint,Marion Larroque,Cyril Ribeyre,Nicole Bec,Christian Larroque,Chantal Décaillet,Kerstin Gari,Angelos Constantinou +7 more
TL;DR: It is found that FANCD2 can interact directly with minichromosome maintenance (MCM) proteins and is an effector of ATR signaling implicated in a general replisome surveillance mechanism that is necessary for sustaining cell proliferation and attenuating carcinogenesis.
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Inhibition of CD39 Enzymatic Function at the Surface of Tumor Cells Alleviates Their Immunosuppressive Activity
Jérémy Bastid,Anne Regairaz,Nathalie Bonnefoy,Cécile Dejou,Jérôme Giustiniani,Caroline Laheurte,Stéphanie Cochaud,Emilie Laprevotte,Elisa Funck-Brentano,Patrice Hemon,Laurent Gros,Nicole Bec,Christian Larroque,Gilles Alberici,Armand Bensussan,Jean-François Eliaou +15 more
TL;DR: Interference with the CD39–adenosine pathway may represent a novel immunotherapeutic strategy for inhibiting tumor cell–mediated immunosuppression.
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Reaction of neuronal nitric-oxide synthase with oxygen at low temperature. Evidence for reductive activation of the oxy-ferrous complex by tetrahydrobiopterin.
TL;DR: It is suggested that the reduction of the oxyferroheme complex may be the main function of BH4 in NOS catalysis.
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Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cells
Nadia Vie,Virginie Copois,Caroline Bascoul-Mollevi,Vincent Denis,Nicole Bec,Bruno Robert,Caroline Fraslon,Emmanuel Conseiller,Franck Molina,Christian Larroque,Pierre Martineau,Maguy Del Rio,Céline Gongora +12 more
TL;DR: Results show that an enzyme playing a role in the L-serine biosynthesis could be implicated in colon cancer progression and chemoresistance and indicate that PSAT1 represents a new interesting target for CRC therapy.