C
Cynthia Levy
Researcher at University of Miami
Publications - 197
Citations - 4494
Cynthia Levy is an academic researcher from University of Miami. The author has contributed to research in topics: Primary sclerosing cholangitis & Medicine. The author has an hindex of 30, co-authored 150 publications receiving 3424 citations. Previous affiliations of Cynthia Levy include Veterans Health Administration & Mayo Clinic.
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Journal ArticleDOI
Patient Age, Sex, and Inflammatory Bowel Disease Phenotype Associate With Course of Primary Sclerosing Cholangitis
Tobias J. Weismüller,Tobias J. Weismüller,Palak J. Trivedi,Annika Bergquist,Mohamad Imam,Mohamad Imam,Henrike Lenzen,Cyriel Y. Ponsioen,Kristian Holm,Daniel Gotthardt,Martti Färkkilä,Hanns-Ulrich Marschall,Douglas Thorburn,Rinse K. Weersma,Johan Fevery,Tobias Mueller,Olivier Chazouillères,Kornelius Schulze,Konstantinos N. Lazaridis,Sven Almer,Stephen P. Pereira,Cynthia Levy,Andrew Mason,Sigrid Næss,Sigrid Næss,Christopher L. Bowlus,Annarosa Floreani,Emina Halilbasic,Kidist K. Yimam,Piotr Milkiewicz,Piotr Milkiewicz,Ulrich Beuers,Dep Huynh,Albert Parés,Christine N. Manser,George N. Dalekos,Bertus Eksteen,Pietro Invernizzi,Christoph P. Berg,Gabi I. Kirchner,Christoph Sarrazin,Vincent Zimmer,Luca Fabris,Felix Braun,Marco Marzioni,Brian D. Juran,Karouk Said,Christian Rupp,Kalle Jokelainen,Maria Benito de Valle,Francesca Saffioti,Angela Cheung,Michael Trauner,Christoph Schramm,Roger W. Chapman,Roger W. Chapman,Tom H. Karlsen,Tom H. Karlsen,Erik Schrumpf,Erik Schrumpf,Christian P. Strassburg,Michael P. Manns,Keith D. Lindor,Keith D. Lindor,Gideon M. Hirschfield,Bettina E. Hansen,Bettina E. Hansen,Bettina E. Hansen,Kirsten Muri Boberg,Kirsten Muri Boberg +69 more
TL;DR: In an analysis of data from individual patients with PSC worldwide, significant variation in clinical course associated with age at diagnosis, sex, and ductal and IBD subtypes is found.
Journal ArticleDOI
The Value of Serum CA 19-9 in Predicting Cholangiocarcinomas in Patients with Primary Sclerosing Cholangitis
Cynthia Levy,James F. Lymp,Paul Angulo,Gregory J. Gores,Nicholas F. LaRusso,Keith D. Lindor,Keith D. Lindor +6 more
TL;DR: The positive predictive value of an elevated CA 19-9 was 56.6%; only advanced cases were detected by this method.
Journal ArticleDOI
International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways
Heather J. Cordell,Younghun Han,George F. Mells,Yafang Li,Gideon M. Hirschfield,Casey S. Greene,Gang Xie,Brian D. Juran,Dakai Zhu,David C. Qian,James A B Floyd,James A B Floyd,Katherine I. Morley,Katherine I. Morley,Daniele Prati,Ana Lleo,Daniele Cusi,Daniele Cusi,M. Eric Gershwin,Carl A. Anderson,Konstantinos N. Lazaridis,Pietro Invernizzi,Michael F. Seldin,Richard Sandford,Christopher I. Amos,Katherine A. Siminovitch,Erik M. Schlicht,Craig Lammert,Elizabeth J. Atkinson,Landon L. Chan,Mariza de Andrade,Tobias Balschun,Andrew Mason,Robert P. Myers,Jinyi Zhang,Piotr Milkiewicz,Jia Qu,Joseph A. Odin,Velimir A. Luketic,Bruce R. Bacon,Henry C. Bodenheimer,Valentina Liakina,Catherine Vincent,Cynthia Levy,Peter K. Gregersen,Piero Luigi Almasio,Domenico Alvaro,Pietro Andreone,Angelo Andriulli,Cristina Barlassina,Pier Maria Battezzati,Antonio Benedetti,Francesca Bernuzzi,Ilaria Bianchi,Maria Consiglia Bragazzi,Maurizia Rossana Brunetto,Savino Bruno,Giovanni Casella,Barbara Coco,Agostino Colli,Massimo Colombo,Silvia Colombo,Carmela Cursaro,Lory Saveria Crocè,Andrea Crosignani,Maria Francesca Donato,Gianfranco Elia,Luca Fabris,Carlo Ferrari,Annarosa Floreani,Barbara Foglieni,R. Fontana,Andrea Galli,Roberta Lazzari,Fabio Salvatore Macaluso,Federica Malinverno,Fabio Marra,Marco Marzioni,Alberto Mattalia,Renzo Montanari,Lorenzo Morini,Filomena Morisco,S. Mousa Hani,Luigi Muratori,Paolo Muratori,Grazia Anna Niro,Vincenzo Palmieri,Antonio Picciotto,Mauro Podda,Piero Portincasa,Vincenzo Ronca,Floriano Rosina,Sonia Rossi,Ilaria Sogno,Giancarlo Spinzi,M. Spreafico,Mario Strazzabosco,Mario Strazzabosco,Sonia Tarallo,Mirko Tarocchi,Claudio Tiribelli,Pierluigi Toniutto,Maria Vinci,Massimo Zuin,Chin Lye Ch'ng,Mesbah Rahman,Tom Yapp,Richard Sturgess,Chris Healey,Marek Czajkowski,Anton V J Gunasekera,Pranab Gyawali,Purushothaman Premchand,Kapil Kapur,Richard Marley,Graham R. Foster,Alan Watson,Aruna Dias,Javaid Subhani,Rory Harvey,Roger McCorry,David Ramanaden,Jaber Gasem,Richard Evans,Thiriloganathan Mathialahan,Christopher Shorrock,George Lipscomb,Paul Southern,Jeremy Tibble,David Gorard,Altaf Palegwala,Susan Jones,Marco Carbone,Mohamed Dawwas,Graeme J.M. Alexander,Sunil Dolwani,Martin Prince,Matthew Foxton,David A Elphick,H.C. Mitchison,Ian Gooding,Mazn Karmo,Sushma Saksena,Mike Mendall,Minesh Patel,Roland Ede,Andrew Austin,Joanna Sayer,Lorraine Hankey,Christopher Hovell,N Fisher,M J Carter,M J Carter,Konrad Koss,Andrzej Piotrowicz,Charles Grimley,David E. Neal,Guan Lim,Sass Levi,Aftab Ala,Andrea Broad,Athar Saeed,Gordon Wood,Jonathan C Brown,Mark Wilkinson,Harriet Gordon,John Ramage,Jo Ridpath,Theodore Ngatchu,Bob Grover,Syed Shaukat,Ray Shidrawi,G. Abouda,Faiz Ali,Ian Rees,Imroz Salam,Mark Narain,Ashley Brown,Simon D. Taylor-Robinson,Simon Williams,Leonie Grellier,Paul R. Banim,Debasish Das,Andrew Chilton,Michael A. Heneghan,Howard Curtis,Markus Gess,Ian Drake,M. Aldersley,M. Aldersley,Mervyn H. Davies,Mervyn H. Davies,Rebecca Jones,Rebecca Jones,Alastair McNair,Raj Srirajaskanthan,Maxton Pitcher,Maxton Pitcher,Sambit Sen,George Bird,Adrian Barnardo,Paul Kitchen,Kevin Yoong,Oza Chirag,Nurani Sivaramakrishnan,George MacFaul,David Jones,Amir Shah,Chris D. Evans,Subrata Saha,Katharine Pollock,Peter Bramley,Ashis Mukhopadhya,Andrew G. Fraser,Peter R. Mills,Christopher Shallcross,Stewart Campbell,Andrew Bathgate,Alan Shepherd,John F. Dillon,Simon M. Rushbrook,Robert Przemioslo,Christopher Macdonald,Jane Metcalf,Udi Shmueli,Andrew Davis,Asifabbas Naqvi,Thomas Lee,Dyder Stephen,Dyder Stephen,Jane Collier,Howard Klass,Mary Ninkovic,Matthew E. Cramp,Nicholas Sharer,Richard Aspinall,Patrick Goggin,Deb Ghosh,Andrew C. Douds,Barbara Hoeroldt,Jonathan Booth,Earl J. Williams,Hyder Hussaini,William Stableforth,Reuben Ayres,Douglas Thorburn,Eileen Marshall,Andrew K. Burroughs,Steven Mann,Martin Lombard,Paul G. Richardson,Imran Patanwala,Julia Maltby,Matthew J Brookes,Ray Mathew,Samir Vyas,Saket Singhal,Dermot Gleeson,Sharat Misra,Jeff Butterworth,Keith George,Tim Harding,Andrew Douglass,Simon Panter,Jeremy Shearman,Gary Bray,Graham Butcher,Daniel M. Forton,John McLindon,M. L. Cowan,Gregory Whatley,Aditya Mandal,Hemant Gupta,Pradeep Sanghi,Sanjiv Jain,S.P. Pereira,Geeta Prasad,Gill Watts,Mark Wright,James Neuberger,Fiona H. Gordon,Esther Unitt,Allister Grant,Toby E. S. Delahooke,Andrew D. Higham,Alison M. Brind,Mark Cox,Subramaniam Ramakrishnan,Alistair King,Carole Collins,Simon Whalley,Andy Li,Jocelyn Fraser,Andrew Bell,Voi Shim Wong,Amit Singhal,Ian Gee,Yeng Ang,Rupert Ransford,James Gotto,Charles Millson,Jane Bowles,Caradog Thomas,Melanie Harrison,Roman Galaska,Jennie Kendall,Jessica Whiteman,Caroline Lawlor,Catherine Gray,Keith Elliott,Caroline Mulvaney-Jones,Lucie Hobson,Greta Van Duyvenvoorde,Alison Loftus,Katie Seward,Ruth Penn,Jane Maiden,Rose Damant,Janeane Hails,Rebecca Cloudsdale,Valeria Silvestre,Sue Glenn,Eleanor Dungca,Natalie Wheatley,Helen Doyle,Melanie Kent,Caroline Hamilton,Delyth Braim,Helen Wooldridge,Rachel Abrahams,Alison Paton,Nicola Lancaster,Andrew Gibbins,Karen Hogben,Phillipa Desousa,Phillipa Desousa,Florin Muscariu,Janine Musselwhite,Alexandra McKay,Laiting Tan,Carole Foale,Jacqueline Brighton,Kerry Flahive,Estelle Nambela,Paula Townshend,Christopher B. Ford,Sophie Holder,Caroline Palmer,James Featherstone,Mariam Nasseri,Joy Sadeghian,Bronwen Williams,Carol Thomas,Sally Ann Rolls,Abigail Hynes,Claire Duggan,Sarah Jones,Mary M.E. Crossey,Glynis Stansfield,Carolyn MacNicol,Joy Wilkins,Elva Wilhelmsen,Parizade Raymode,Hye Jeong Lee,Emma Durant,Rebecca Bishop,Rebecca Bishop,Noma Ncube,Sherill Tripoli,Sherill Tripoli,Rebecca Casey,Caroline Cowley,Richard A. Miller,Kathryn Houghton,Samantha Ducker,Fiona Wright,Bridget Bird,Gwen Baxter,Janie Keggans,Maggie Hughes,Emma Grieve,Karin Young,D. Williams,Kate Ocker,Frances Hines,Kirsty G. Martin,Caron Innes,Caron Innes,Talal Valliani,Helen Fairlamb,Sarah Thornthwaite,Anne Eastick,Elizabeth Tanqueray,Jennifer Morrison,Becky Holbrook,Julie Browning,Kirsten Walker,Susan Congreave,Susan Congreave,Juliette Verheyden,Juliette Verheyden,Susan Slininger,Susan Slininger,Lizzie Stafford,Denise O'Donnell,Mark A. Ainsworth,Susan Lord,Linda Kent,Linda March,Christine Dickson,Diane Simpson,Beverley Longhurst,Maria Hayes,Ervin Shpuza,Nikki White,Sarah Besley,Sallyanne Pearson,Alice Wright,L. Jones,Emma Gunter,H. Dewhurst,Anna Fouracres,Liz Farrington,Lyn Graves,Suzie Marriott,Marina Leoni,David Tyrer,Kate Martin,Lola Dali-Kemmery,Victoria Lambourne,Marie Green,Dawn Sirdefield,Kelly Amor,Julie Colley,Bal Shinder,Jayne Jones,Marisa Mills,Mandy Carnahan,Natalie Taylor,Kerenza Boulton,Julie Tregonning,Carly Brown,Gayle Clifford,Emily Archer,Maria Hamilton,Janette Curtis,Tracey Shewan,Susan Walsh,Karen Warner,Kimberley Netherton,McDonald Mupudzi,Bridget Gunson,Jane Gitahi,Denise Gocher,Sally Batham,Hilary Pateman,Senayon Desmennu,Jill Conder,Darren Clement,Susan Gallagher,Jacky Orpe,Puiching Chan,Lynn Currie,Lynn O'Donohoe,Metod Oblak,Lisa Morgan,Marie Quinn,Isobel Amey,Yolanda Baird,Donna Cotterill,Lourdes Cumlat,Louise Winter,Sandra Greer,Katie Spurdle,Joanna Allison,Simon Dyer,Helen Sweeting,Jean Kordula +477 more
TL;DR: This work discovers and validate six previously unknown risk loci for PBC and used pathway analysis to identify JAK-STAT/IL12/IL27 signalling and cytokine–cytokine pathways, for which relevant therapies exist.
Journal ArticleDOI
Variants at IRF5-TNPO3 , 17q12-21 and MMEL1 are associated with primary biliary cirrhosis
Gideon M. Hirschfield,Gideon M. Hirschfield,Xiangdong Liu,Younghun Han,Ivan P. Gorlov,Yan Lu,Chun Xu,Yue Lu,Wei V. Chen,Brian D. Juran,Catalina Coltescu,Andrew Mason,Piotr Milkiewicz,Robert P. Myers,Joseph A. Odin,Velimir A. Luketic,Danute Speiciene,Catherine Vincent,Cynthia Levy,Peter K. Gregersen,Jinyi Zhang,E. Jenny Heathcote,E. Jenny Heathcote,Konstantinos N. Lazaridis,Christopher I. Amos,Katherine A. Siminovitch +25 more
TL;DR: Genotyped individuals with primary biliary cirrhosis and unaffected controls for suggestive risk loci and showed that a single variant accounts for the IRF5-TNPO3 association, confirming genetic overlap among such diseases.
Journal ArticleDOI
Pilot study: fenofibrate for patients with primary biliary cirrhosis and an incomplete response to ursodeoxycholic acid
Cynthia Levy,Joy Peter,David R. Nelson,Jill C. Keach,Janice L. Petz,Roniel Cabrera,Virginia Clark,Roberto J. Firpi,Giuseppe Morelli,Consuelo Soldevila-Pico,Keith D. Lindor +10 more
TL;DR: Aliment Pharmacol Ther 2011; 33: 235–242