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Christie Brinkley
Researcher at Duke University
Publications - 9
Citations - 328
Christie Brinkley is an academic researcher from Duke University. The author has contributed to research in topics: Virus & Simian immunodeficiency virus. The author has an hindex of 6, co-authored 9 publications receiving 248 citations.
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Journal ArticleDOI
An Exome Sequencing Study to Assess the Role of Rare Genetic Variation in Pulmonary Fibrosis.
Slavé Petrovski,Slavé Petrovski,Jamie L. Todd,Jamie L. Todd,Michael T. Durheim,Michael T. Durheim,Quanli Wang,Jason W. Chien,Francine L. Kelly,Courtney W. Frankel,Caroline Mebane,Zhong Ren,Joshua Bridgers,Thomas J. Urban,Colin D. Malone,Ashley Finlen Copeland,Christie Brinkley,Andrew S. Allen,Thomas G. O'Riordan,John G. McHutchison,Scott M. Palmer,Scott M. Palmer,David Goldstein +22 more
TL;DR: The idea that telomere dysfunction is involved in IPF pathogenesis is supported, as whole‐exome sequencing data identified TERT, RTEL1, and PARN—three telomeres‐related genes previously implicated in familial pulmonary fibrosis—as significant contributors to sporadic IPF.
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Association of HIV-1 Envelope-Specific Breast Milk IgA Responses with Reduced Risk of Postnatal Mother-to-Child Transmission of HIV-1
Justin Pollara,Erin McGuire,Genevieve G. Fouda,Wes Rountree,Josh A Eudailey,R. Glenn Overman,Kelly E. Seaton,Aaron Deal,R. Whitney Edwards,Gerald Tegha,Deborah Kamwendo,Jacob Kumwenda,Julie A. E. Nelson,Hua-Xin Liao,Christie Brinkley,Thomas N. Denny,Christina Ochsenbauer,Sascha R. Ellington,Caroline C. King,Denise J. Jamieson,Charles van der Horst,Athena P. Kourtis,Georgia D. Tomaras,Guido Ferrari,Sallie R. Permar +24 more
TL;DR: A protective role for mucosal HIV-1 envelope-specific IgA responses in the context of postnatal virus transmission is suggested, which supports further investigations into the mechanisms by which mucosal IgA reduces risk of HIV- 1 transmission via breast milk and into immune interventions aimed at enhancing this response.
Journal ArticleDOI
Development of a contemporary globally diverse HIV viral panel by the EQAPOL program
Ana M. Sanchez,C. Todd DeMarco,Bhavna Hora,Sarah Keinonen,Yue Chen,Christie Brinkley,Mars Stone,Leslie H. Tobler,Sheila M. Keating,Marco Schito,Michael P. Busch,Feng Gao,Thomas N. Denny +12 more
TL;DR: The EQAPOL Viral Diversity panel is an invaluable collection of well-characterized reagents available to the scientific community, including researchers, epidemiologists, and commercial manufacturers of diagnostics and pharmaceuticals to support HIV research, as well as diagnostic and vaccine development.
Journal ArticleDOI
Infection of monkeys by simian-human immunodeficiency viruses with transmitted/founder clade C HIV-1 envelopes.
Mohammed Asmal,Corinne Luedemann,Christy L. Lavine,Linh Mach,Harikrishnan Balachandran,Christie Brinkley,Thomas N. Denny,Mark G. Lewis,Hanne Anderson,Ranajit Pal,Devin Sok,Khoa Le,Matthias Pauthner,Beatrice H. Hahn,George M. Shaw,Michael S. Seaman,Norman L. Letvin,Dennis R. Burton,Joseph Sodroski,Barton F. Haynes,Sampa Santra +20 more
TL;DR: Three new clade C T/F SHIVs are developed that are mucosally transmissible and are neutralized by sCD4 and several HIV-1 broadly neutralizing antibodies, and exhibit low Env reactivity and a Tier 2 neutralization sensitivity.
Journal ArticleDOI
The Diacetyl-Exposed Human Airway Epithelial Secretome: New Insights into Flavoring-Induced Airways Disease
David M. Brass,William M. Gwinn,Ashlee M. Valente,Francine L. Kelly,Christie Brinkley,Andrew E. Nagler,M. Arthur Moseley,Daniel L. Morgan,Scott M. Palmer,Matthew W. Foster +9 more
TL;DR: The ordered changes in protein expression suggest that the airway epithelial response to diacetyl may contribute to BO pathogenesis.