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Claudine Médigue
Researcher at French Alternative Energies and Atomic Energy Commission
Publications - 24
Citations - 1879
Claudine Médigue is an academic researcher from French Alternative Energies and Atomic Energy Commission. The author has contributed to research in topics: Genome & Plasmid. The author has an hindex of 18, co-authored 24 publications receiving 1669 citations. Previous affiliations of Claudine Médigue include Alternatives & University of Évry Val d'Essonne.
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Journal ArticleDOI
The revisited genome of Pseudomonas putida KT2440 enlightens its value as a robust metabolic chassis.
Eugeni Belda,Eugeni Belda,Ruben G. A. van Heck,Maria Jose Lopez-Sanchez,Stéphane Cruveiller,Valérie Barbe,Claire M. Fraser,Hans-Peter Klenk,Jörn Petersen,Anne Morgat,Pablo I. Nikel,David Vallenet,Zoé Rouy,Agnieszka Sekowska,Vitor A. P. Martins dos Santos,Víctor de Lorenzo,Antoine Danchin,Claudine Médigue +17 more
TL;DR: The resulting examination not only accounts for some of the known stress tolerance traits known in P. putida but also recognizes the capacity of this bacterium to perform difficult redox reactions, thereby multiplying its value as a platform microorganism for industrial biotechnology.
Journal ArticleDOI
Mutation rate dynamics in a bacterial population reflect tension between adaptation and genetic load.
Sébastien Wielgoss,Jeffrey E. Barrick,Olivier Tenaillon,Olivier Tenaillon,Michael J. Wiser,W. James Dittmar,Stéphane Cruveiller,Béatrice Chane-Woon-Ming,Claudine Médigue,Richard E. Lenski,Dominique Schneider +10 more
TL;DR: It is found that an adapting Escherichia coli population that first evolved a mutT hypermutator phenotype was later invaded by two independent lineages with mutY mutations that reduced genome-wide mutation rates.
Journal ArticleDOI
Genomes of three tomato pathogens within the Ralstonia solanacearum species complex reveal significant evolutionary divergence.
Benoit Remenant,Bénédicte Coupat-Goutaland,Alice Guidot,Gilles Cellier,Emmanuel Wicker,Caitilyn Allen,Mark Fegan,Olivier Pruvost,Mounira Elbaz,Alexandra Calteau,Gregory Salvignol,Damien Mornico,Sophie Mangenot,Valérie Barbe,Claudine Médigue,Philippe Prior +15 more
TL;DR: The Ralstonia solanacearum species complex includes thousands of strains pathogenic to an unusually wide range of plant species and how the bacteria survive in many different habitats as mentioned in this paper.
Journal ArticleDOI
The Entomopathogenic Bacterial Endosymbionts Xenorhabdus and Photorhabdus: Convergent Lifestyles from Divergent Genomes
John M. Chaston,Garret Suen,Sarah L. Tucker,Aaron W. Andersen,Archna Bhasin,Edna Bode,Helge B. Bode,Alexander O. Brachmann,Charles E. Cowles,Kimberly N. Cowles,Creg Darby,Limaris de Léon,Kevin Drace,Zijin Du,Alain Givaudan,Alain Givaudan,Erin E. H. Tran,Kelsea A. Jewell,Jennifer J. Knack,Karina Krasomil-Osterfeld,Ryan Kukor,Anne Lanois,Anne Lanois,Phil Latreille,Nancy K. Leimgruber,Carolyn M. Lipke,Renyi Liu,Xiaojun Lu,Eric C. Martens,Pradeep Reddy Marri,Claudine Médigue,Megan Menard,Nancy M. Miller,Nydia Morales-Soto,Stacie Norton,Jean Claude Ogier,Jean Claude Ogier,Samantha S. Orchard,Dongjin Park,Youngjin Park,Barbara A. Qurollo,Darby R. Sugar,Gregory R. Richards,Zoé Rouy,Brad Slominski,Kathryn Slominski,Holly Snyder,Brian Tjaden,Ransome van der Hoeven,Roy D. Welch,Cathy Wheeler,Bosong Xiang,Brad Barbazuk,Sophie Gaudriault,Sophie Gaudriault,Brad Goodner,Steven C. Slater,Steven Forst,Barry S. Goldman,Heidi Goodrich-Blair +59 more
TL;DR: Findings indicate that evolutionary changes shaped by symbiotic interactions can follow different routes to achieve similar end points.
Journal ArticleDOI
Mutation Rate Inferred From Synonymous Substitutions in a Long-Term Evolution Experiment With Escherichia coli
Sébastien Wielgoss,Sébastien Wielgoss,Jeffrey E. Barrick,Olivier Tenaillon,Olivier Tenaillon,Stéphane Cruveiller,Béatrice Chane-Woon-Ming,Claudine Médigue,Richard E. Lenski,Dominique Schneider,Dominique Schneider +10 more
TL;DR: This work sequenced 19 Escherichia coli genomes from a 40,000-generation evolution experiment and directly inferred the point-mutation rate based on the accumulation of synonymous substitutions, which represents the most accurate measure of bacterial base-substitution rates available to date.