C
Cosetta Minelli
Researcher at National Institutes of Health
Publications - 159
Citations - 11620
Cosetta Minelli is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Population & Mendelian randomization. The author has an hindex of 48, co-authored 146 publications receiving 8914 citations. Previous affiliations of Cosetta Minelli include Mario Negri Institute for Pharmacological Research & University of Brescia.
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Journal ArticleDOI
New loci associated with kidney function and chronic kidney disease
Anna Köttgen,Anna Köttgen,Cristian Pattaro,Carsten A. Böger,Christian Fuchsberger,Matthias Olden,Nicole L. Glazer,Afshin Parsa,Xiaoyi Gao,Qiong Yang,Albert V. Smith,Jeffrey R. O'Connel,Man Li,Helena Schmidt,Toshiko Tanaka,Toshiko Tanaka,Aaron Isaacs,Shamika Ketkar,Shih-Jen Hwang,Andrew D. Johnson,Abbas Dehghan,Alexander Teumer,Guillaume Paré,Elizabeth J. Atkinson,Tanja Zeller,Kurt Lohman,Marilyn C. Cornelis,Nicole Probst-Hensch,Nicole Probst-Hensch,Florian Kronenberg,Anke Tönjes,Caroline Hayward,Thor Aspelund,Gudny Eiriksdottir,Lenore J. Launer,Tamara B. Harris,Evadnie Rampersaud,Braxton D. Mitchel,Dan E. Arking,Eric Boerwinkle,Maksim Struchalin,Margherita Cavalieri,Andrew B. Singleton,Francesco Giallauria,Jeffrey Metter,Ian H. de Boer,Talin Haritunians,Thomas Lumley,David S. Siscovick,Bruce M. Psaty,M. CarolaZillikens,Ben A. Oostra,Mary F. Feitosa,Michael A. Province,Mariza de Andrade,Stephen T. Turner,Arne Schillert,Andreas Ziegler,Philipp S. Wild,Renate B. Schnabel,Sandra Wilde,Thomas Münzel,Tennille S. Leak,Thomas Illig,Norman Klopp,Christa Meisinger,H.-Erich Wichmann,Wolfgang Koenig,Lina Zgaga,Tatijana Zemunik,Ivana Kolcic,Cosetta Minelli,Frank B. Hu,Åsa Johansson,Wilmar Igl,Ghazal Zaboli,Sarah H. Wild,Alan F. Wright,Harry Campbell,David Ellinghaus,Stefan Schreiber,Yurii S. Aulchenko,Janine F. Felix,Fernando Rivadeneira,André G. Uitterlinden,Albert Hofman,Medea Imboden,Medea Imboden,Dorothea Nitsch,Anita Brandstätter,Barbara Kollerits,Lyudmyla Kedenko,Reedik Mägi,Michael Stumvoll,Peter Kovacs,Mladen Boban,Susan Campbell,Karlhans Endlich,Henry Völzke,Heyo K. Kroemer,Matthias Nauck,Uwe Völker,Ozren Polasek,Veronique Vitart,Sunita Badola,Alex Parker,Paul M. Ridker,Sharon L.R. Kardia,Stefan Blankenberg,Yongmei Liu,Gary C. Curhan,Andre Franke,Thierry Rochat,Bernhard Paulweber,Inga Prokopenko,Wei Wang,Wei Wang,Vilmundur Gudnason,Alan R. Shuldine,Josef Coresh,Reinhold E. Schmidt,Luigi Ferrucci,Michael G. Shlipak,Cornelia M. van Duijn,Ingrid B. Borecki,Bernhard K. Krämer,Igor Rudan,Ulf Gyllensten,James F. Wilson,Jacqueline C. M. Witteman,Peter P. Pramstaller,Rainer Rettig,Nicholas D. Hastie,Daniel I. Chasman,Wen Hong L. Kao,Iris M. Heid,Caroline S. Fox,Caroline S. Fox +137 more
TL;DR: The CKDGen consortium performed a meta-analysis of genome-wide association data in 67,093 individuals of European ancestry to identify new susceptibility loci for reduced renal function as estimated by serum creatinine, serum cystatin c and CKD.
Journal ArticleDOI
Assessing the suitability of summary data for two-sample Mendelian randomization analyses using MR-Egger regression: the role of the I2 statistic
Jack Bowden,Fabiola Del Greco M,Cosetta Minelli,George Davey Smith,Nuala A. Sheehan,John R. Thompson +5 more
TL;DR: The proposed approach for a two-sample summary data MR analysis to estimate the causal effect of low-density lipoprotein on heart disease risk is demonstrated and care must be taken to assess the NOME assumption via the IGX2 statistic before implementing standard MR-Egger regression in the two- sample summary data context.
Journal ArticleDOI
A framework for the investigation of pleiotropy in two-sample summary data Mendelian randomization
Jack Bowden,Fabiola Del Greco M,Cosetta Minelli,George Davey Smith,Nuala A. Sheehan,John F. Thompson +5 more
TL;DR: How established methods of meta‐regression and random effects modelling from mainstream meta‐analysis are being adapted to perform MR analyses are clarified, and the ability of two popular random effects models to provide robustness to pleiotropy under the IVW approach is investigated.
Journal ArticleDOI
Epidemiology and outcome of acute lung injury in European intensive care units. Results from the ALIVE study.
Christian Brun-Buisson,Cosetta Minelli,Guido Bertolini,Luca Brazzi,Jorge Pimentel,K. Lewandowski,Julian Bion,Jacques-André Romand,Jesús Villar,Adalbjörn Thorsteinsson,Pierre Damas,Apostolos Armaganidis,François Lemaire +12 more
TL;DR: One third of patients presented with mild ALI, but more than half rapidly evolved to acute respiratory distress syndrome (ARDS), confirming the grading of severity between the two forms of the syndrome.
Journal ArticleDOI
Guidelines for performing Mendelian randomization investigations.
Stephen Burgess,George Davey Smith,Neil M Davies,Frank Dudbridge,Dipender Gill,M. Maria Glymour,Fernando Pires Hartwig,Fernando Pires Hartwig,Michael V. Holmes,Michael V. Holmes,Cosetta Minelli,Caroline L Relton,Evropi Theodoratou,Evropi Theodoratou +13 more
TL;DR: The guidelines are divided into nine sections: motivation and scope, data sources, choice of genetic variants, variant harmonization, primary analysis, supplementary and sensitivity analyses, data presentation, and interpretation.