G
Ghazal Zaboli
Researcher at Uppsala University
Publications - 19
Citations - 3272
Ghazal Zaboli is an academic researcher from Uppsala University. The author has contributed to research in topics: Population & Genome-wide association study. The author has an hindex of 18, co-authored 19 publications receiving 3044 citations. Previous affiliations of Ghazal Zaboli include Karolinska University Hospital & Karolinska Institutet.
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Journal ArticleDOI
New loci associated with kidney function and chronic kidney disease
Anna Köttgen,Anna Köttgen,Cristian Pattaro,Carsten A. Böger,Christian Fuchsberger,Matthias Olden,Nicole L. Glazer,Afshin Parsa,Xiaoyi Gao,Qiong Yang,Albert V. Smith,Jeffrey R. O'Connel,Man Li,Helena Schmidt,Toshiko Tanaka,Toshiko Tanaka,Aaron Isaacs,Shamika Ketkar,Shih-Jen Hwang,Andrew D. Johnson,Abbas Dehghan,Alexander Teumer,Guillaume Paré,Elizabeth J. Atkinson,Tanja Zeller,Kurt Lohman,Marilyn C. Cornelis,Nicole Probst-Hensch,Nicole Probst-Hensch,Florian Kronenberg,Anke Tönjes,Caroline Hayward,Thor Aspelund,Gudny Eiriksdottir,Lenore J. Launer,Tamara B. Harris,Evadnie Rampersaud,Braxton D. Mitchel,Dan E. Arking,Eric Boerwinkle,Maksim Struchalin,Margherita Cavalieri,Andrew B. Singleton,Francesco Giallauria,Jeffrey Metter,Ian H. de Boer,Talin Haritunians,Thomas Lumley,David S. Siscovick,Bruce M. Psaty,M. CarolaZillikens,Ben A. Oostra,Mary F. Feitosa,Michael A. Province,Mariza de Andrade,Stephen T. Turner,Arne Schillert,Andreas Ziegler,Philipp S. Wild,Renate B. Schnabel,Sandra Wilde,Thomas Münzel,Tennille S. Leak,Thomas Illig,Norman Klopp,Christa Meisinger,H.-Erich Wichmann,Wolfgang Koenig,Lina Zgaga,Tatijana Zemunik,Ivana Kolcic,Cosetta Minelli,Frank B. Hu,Åsa Johansson,Wilmar Igl,Ghazal Zaboli,Sarah H. Wild,Alan F. Wright,Harry Campbell,David Ellinghaus,Stefan Schreiber,Yurii S. Aulchenko,Janine F. Felix,Fernando Rivadeneira,André G. Uitterlinden,Albert Hofman,Medea Imboden,Medea Imboden,Dorothea Nitsch,Anita Brandstätter,Barbara Kollerits,Lyudmyla Kedenko,Reedik Mägi,Michael Stumvoll,Peter Kovacs,Mladen Boban,Susan Campbell,Karlhans Endlich,Henry Völzke,Heyo K. Kroemer,Matthias Nauck,Uwe Völker,Ozren Polasek,Veronique Vitart,Sunita Badola,Alex Parker,Paul M. Ridker,Sharon L.R. Kardia,Stefan Blankenberg,Yongmei Liu,Gary C. Curhan,Andre Franke,Thierry Rochat,Bernhard Paulweber,Inga Prokopenko,Wei Wang,Wei Wang,Vilmundur Gudnason,Alan R. Shuldine,Josef Coresh,Reinhold E. Schmidt,Luigi Ferrucci,Michael G. Shlipak,Cornelia M. van Duijn,Ingrid B. Borecki,Bernhard K. Krämer,Igor Rudan,Ulf Gyllensten,James F. Wilson,Jacqueline C. M. Witteman,Peter P. Pramstaller,Rainer Rettig,Nicholas D. Hastie,Daniel I. Chasman,Wen Hong L. Kao,Iris M. Heid,Caroline S. Fox,Caroline S. Fox +137 more
TL;DR: The CKDGen consortium performed a meta-analysis of genome-wide association data in 67,093 individuals of European ancestry to identify new susceptibility loci for reduced renal function as estimated by serum creatinine, serum cystatin c and CKD.
Journal ArticleDOI
Genome-wide association study identifies five loci associated with lung function.
Emmanouela Repapi,Ian Sayers,Louise V. Wain,Paul Burton,Toby Johnson,Ma'en Obeidat,Jing Hua Zhao,Adaikalavan Ramasamy,Guangju Zhai,Veronique Vitart,Jennifer E. Huffman,Wilmar Igl,E Albrecht,Panagiotis Deloukas,John Henderson,Raquel Granell,Wendy L. McArdle,Alicja R. Rudnicka,Inês Barroso,Loos Rjf.,Nicholas J. Wareham,Linda Mustelin,Taina Rantanen,Ida Surakka,Ida Surakka,Medea Imboden,H E Wichmann,Ivica Grković,Stipan Janković,Lina Zgaga,Hartikainen A-L.,Hartikainen A-L.,Hartikainen A-L.,Leena Peltonen,Leena Peltonen,Leena Peltonen,Ulf Gyllensten,Åsa Johansson,Ghazal Zaboli,Harry Campbell,Sarah H. Wild,James F. Wilson,Sven Gläser,Georg Homuth,Henry Völzke,Massimo Mangino,Nicole Soranzo,Nicole Soranzo,Tim D. Spector,Ozren Polasek,Igor Rudan,Igor Rudan,Alan F. Wright,Markku Heliövaara,Samuli Ripatti,Samuli Ripatti,Anneli Pouta,Åsa Torinsson Naluai,Olin A-C.,Kjell Torén,Mark E. Cooper,Alan James,Lyle J. Palmer,Lyle J. Palmer,Aroon D. Hingorani,S.G. Wannamethee,Peter H. Whincup,George Davey Smith,Shah Ebrahim,Tricia M. McKeever,Ian D. Pavord,Andrew K. MacLeod,Andrew D. Morris,David J. Porteous,Cyrus Cooper,Cyrus Cooper,Elaine M. Dennison,Seif O. Shaheen,Stefan Karrasch,E Schnabel,Holger Schulz,H Grallert,Nabila Bouatia-Naji,Jérôme Delplanque,Philippe Froguel,Philippe Froguel,John D Blakey,John Britton,Richard W Morris,John W. Holloway,Debbie A Lawlor,Jennie Hui,Jennie Hui,Fredrik Nyberg,Fredrik Nyberg,Jarvelin M-R.,Catherine Jackson,Mika Kähönen,Jaakko Kaprio,Jaakko Kaprio,Nicole Probst-Hensch,Nicole Probst-Hensch,Beate Koch,Caroline Hayward,David M. Evans,Paul Elliott,Paul Elliott,David P. Strachan,Ian P. Hall,Martin D. Tobin +109 more
TL;DR: Genome-wide association with forced expiratory volume in 1 s (FEV1) and the ratio of FEV1 to forced vital capacity (FVC) in the SpiroMeta consortium offers mechanistic insight into pulmonary function regulation and indicate potential targets for interventions to alleviate respiratory disease.
Journal ArticleDOI
A Comprehensive Evaluation of Potential Lung Function Associated Genes in the SpiroMeta General Population Sample
Ma'en Obeidat,Louise V. Wain,Nick Shrine,Noor Kalsheker,María Soler Artigas,Emmanouela Repapi,Emmanouela Repapi,Paul Burton,Toby Johnson,Adaikalavan Ramasamy,Adaikalavan Ramasamy,Jing Hua Zhao,Guangju Zhai,Jennifer E. Huffman,Veronique Vitart,Eva Albrecht,Wilmar Igl,Anna-Liisa Hartikainen,Anneli Pouta,Gemma Cadby,Gemma Cadby,Jennie Hui,Jennie Hui,Lyle J. Palmer,Lyle J. Palmer,David Hadley,David Hadley,Wendy L. McArdle,Alicja R. Rudnicka,Inês Barroso,Inês Barroso,Ruth J. F. Loos,Nicholas J. Wareham,Massimo Mangino,Nicole Soranzo,Nicole Soranzo,Tim D. Spector,Sven Gläser,Georg Homuth,Henry Völzke,Panos Deloukas,Raquel Granell,John Henderson,Ivica Grković,Stipan Janković,Lina Zgaga,Ozren Polasek,Igor Rudan,Igor Rudan,Alan F. Wright,Harry Campbell,Sarah H. Wild,James F. Wilson,Joachim Heinrich,Medea Imboden,Nicole Probst-Hensch,Nicole Probst-Hensch,Ulf Gyllensten,Åsa Johansson,Ghazal Zaboli,Linda Mustelin,Taina Rantanen,Ida Surakka,Ida Surakka,Jaakko Kaprio,Jaakko Kaprio,Marjo-Riitta Järvelin,Caroline Hayward,David M. Evans,Beate Koch,Arthur W. Musk,Arthur W. Musk,Paul Elliott,David P. Strachan,Martin D. Tobin,Ian Sayers,Ian P. Hall +76 more
TL;DR: Polymorphisms spanning previously associated lung function genes did not show strong evidence for association with lung function measures in the SpiroMeta consortium population of 20,288 individuals from the general population.
Journal ArticleDOI
Meta-analysis identifies multiple loci associated with kidney function–related traits in east Asian populations
Yukinori Okada,Xueling Sim,Xueling Sim,Min Jin Go,Jer-Yuarn Wu,Jer-Yuarn Wu,Dongfeng Gu,Fumihiko Takeuchi,Atsushi Takahashi,Shiro Maeda,Tatsuhiko Tsunoda,Peng Chen,Su Chi Lim,Su Chi Lim,Tien Yin Wong,Tien Yin Wong,Tien Yin Wong,Jianjun Liu,Terri L. Young,Tin Aung,Tin Aung,Mark Seielstad,Yik Ying Teo,Yik Ying Teo,Young-Jin Kim,Jong-Young Lee,Bok Ghee Han,Daehee Kang,Chien Hsiun Chen,Chien Hsiun Chen,Fuu Jen Tsai,Li-Ching Chang,S. J. Fann,Hao Mei,Dabeeru C. Rao,James E. Hixson,Shufeng Chen,Tomohiro Katsuya,Motohide Isono,Toshio Ogihara,Toshio Ogihara,John C. Chambers,Weihua Zhang,Jaspal S. Kooner,E Albrecht,Kazuhiko Yamamoto,Michiaki Kubo,Yusuke Nakamura,Kamatani Naoyuki,Norihiro Kato,Jiang He,Yuan-Tsong Chen,Yoon Shin Cho,E-Shyong Tai,Toshihiro Tanaka,Graham M. Lord,P. van der Harst,Debbie A Lawlor,Jobanpreet Sehmi,Daniel P. Gale,Mark N. Wass,Kourosh R. Ahmadi,Stephan J. L. Bakker,Jacqui Beckmann,Hjg Bilo,Murielle Bochud,Morris J. Brown,M. J. Caulfield,Jmc Connell,H.T. Cook,Ioana Cotlarciuc,George Davey Smith,R. de Silva,G. Deng,Olivier Devuyst,L. D. Dikkeschei,N. Dimkovic,M. Dockrell,Anna F. Dominiczak,S Ebrahim,Thomas Eggermann,Martin Farrall,L Ferrucci,Juergen Floege,Nita G. Forouhi,Ron T. Gansevoort,X. Han,Bo Hedblad,J. J. van der Heide,Bouke G. Hepkema,Maria P. Hernandez-Fuentes,Elina Hyppönen,Toby Johnson,P. E. De Jong,Nanno Kleefstra,Vasiliki Lagou,Marta Lapsley,Yun Li,Ruth J. F. Loos,Jian'an Luan,Karin Luttropp,Céline Maréchal,Olle Melander,Patricia B. Munroe,Louise Nordfors,Afshin Parsa,Leena Peltonen,B.W.J.H. Penninx,Esperanza Perucha,A Pouta,Inga Prokopenko,Paul Roderick,Aimo Ruokonen,Nilesh J. Samani,Serena Sanna,Martin Schalling,David Schlessinger,Georg Schlieper,Marc A. Seelen,A. R. Shuldiner,Marketa Sjögren,J.H. Smit,Harold Snieder,Nicola Soranzo,Tim D. Spector,Peter Stenvinkel,Michael J.E. Sternberg,R. Swaminathan,L.J. Ubink-Veltmaat,Manuela Uda,Peter Vollenweider,Chris Wallace,Dawn M. Waterworth,Klaus Zerres,Gérard Waeber,Nicholas J. Wareham,Patrick H. Maxwell,Mark I. McCarthy,M-R Jarvelin,Vincent Mooser,G. Abecasis,Liz Lightstone,Jemima Scott,Gerjan Navis,Paul Elliott,Anna Köttgen,C. Pattaro,Carsten A. Böger,Christian Fuchsberger,Matthias Olden,Nicole L. Glazer,X. Gao,Qiong Yang,Albert V. Smith,Jeffery R. O'Connell,Man Li,H. Schmidt,A Isaacs,Shamika Ketkar,Shih-Jen Hwang,Andrew D. Johnson,Abbas Dehghan,A. Teumer,Guillaume Paré,Elizabeth J. Atkinson,Tanja Zeller,Kurt Lohman,Marilyn C. Cornelis,Nicole Probst-Hensch,Florian Kronenberg,A Tönjes,Caroline Hayward,Thor Aspelund,G. Eiriksdottir,L. J. Launer,T.B. Harris,Evandine Rampersaud,B. D. Mitchell,D.E. Arking,Eric Boerwinkle,Maksim Struchalin,Margherita Cavalieri,AB Singleton,Francesco Giallauria,Jeffrey Metter,I. H. de Boer,Talin Haritunians,Thomas Lumley,David S. Siscovick,Bruce M. Psaty,M. C. Zillikens,B.A. Oostra,Mary F. Feitosa,M. A. Province,M. De Andrade,Stephen T. Turner,Arne Schillert,Anette-G. Ziegler,Philipp S. Wild,Renate B. Schnabel,Sandra Wilde,Thomas Münzel,Tennille S. Leak,Thomas Illig,N. Klopp,Christine Meisinger,Heinz Erich Wichmann,Wolfgang Koenig,Lina Zgaga,Tatijana Zemunik,Ivana Kolcic,Cosetta Minelli,Frank B. Hu,Johansson,Wilmar Igl,Ghazal Zaboli,Sarah H. Wild,A. F. Wright,Hannah Campbell,David Ellinghaus,Stuart L. Schreiber,Y S Aulchenko,Janine F. Felix,F. Rivadeneira,A.G. Uitterlinden,A. Hofman,Medea Imboden,Dorothea Nitsch,Anita Brandstätter,Barbara Kollerits,Lyudmyla Kedenko,Reedik Mägi,Michael Stumvoll,Peter Kovacs,Mladen Boban,Sharon Campbell,Karlhans Endlich,Henry Völzke,Heyo K. Kroemer,Matthias Nauck,Uwe Völker,Ozren Polašek,Veronique Vitart,Sunita Badola,Alex Parker,Paul M. Ridker,Sharon L.R. Kardia,Stefan Blankenberg,Yongmei Liu,G. C. Curhan,Andre Franke,Tatiana Rochat,B. Paulweber,W. Wang,Vilmundur Gudnason,Josef Coresh,Reinhold E. Schmidt,Michael G. Shlipak,C M van Duijn,Ingrid B. Borecki,Bernhard K. Krämer,Igor Rudan,Ulf Gyllensten,J.F. Wilson,J. C. M. Witteman,Peter P. Pramstaller,Rainer Rettig,Nicholas D. Hastie,Daniel I. Chasman,W. H. Kao,I. M. Heid,Caroline S. Fox,Jan Krumsiek,Claudia Hundertmark,Giorgio Pistis,Daniela Ruggiero,M. O'seaghdha,T. Haller,Z. Kutalik,Julia Shi,P. S. Middelberg,Angelo L. Gaffo,Nicola Pirastu,Guo Li,Jennifer E. Huffman,Loic Yengo,Jing Hua Zhao,Ayse Demirkan,M. F. Feitosa,Xuan Liu,Giovanni Malerba,Lorna M. Lopez,Xinzhong Li,Marcus E. Kleber,Andrew A. Hicks,Ilja M. Nolte,Åsa Johansson,Federico Murgia,J F Peden,Maristella Steri,Albert Tenesa,Perttu Salo,Massimo Mangino,Lynda M. Rose,Terho Lehtimäki,Owen M. Woodward,Adrienne Tin,Craig Muller,Christopher Oldmeadow,Margus Putku,Darina Czamara,Peter Kraft,Laura Frogheri,Gian Andri Thun,Anne Grotevendt,Gauti Kjartan Gislason,Patrick F. McArdle,Michael Schallert,N. G. Martin,Grant W. Montgomery,David R. Jacobs,Kiang Liu,Pio D'Adamo,S. Ulivi,Jerome I. Rotter,P. Navaro,B. Balkau,Philippe Froguel,Tõnu Esko,Andres Salumets,Kay-Tee Khaw,Claudia Langenberg,Aldi T. Kraja,Qunyuan Zhang,Rodney J. Scott,Elizabeth G. Holliday,Elin Org,Margus Viigimaa,Stefania Bandinelli,Jeffery Metter,Antonio Lupo,Elisabetta Trabetti,Rossella Sorice,Angela Döring,Eva Lattka,Konstantin Strauch,Fabian J. Theis,M. Waldenberger,G. Davies,Alan J. Gow,Marcel Bruinenberg,Ronald P. Stolk,Winkelmann Br,B O Boehm,Susanne Lucae,G. Curhan,Poorva Mudgal,Robert M. Plenge,Laura Portas,Ivana Persico,Mirna Kirin,I. Mateo Leach,W. H. Van Gilst,Anuj Goel,Halit Ongen,A. von Eckardstein,Francesco Cucca,Ramaiah Nagaraja,Maria Grazia Piras,Claudia Schurmann,Klemens Budde,Florian Ernst,Susan M. Farrington,Evropi Theodoratou,A. Jula,M. Perola,V. Salomaa,So-Youn Shin,Cinzia Sala,Mika Kähönen,Jorma Viikari,Christian Hengstenberg,Christopher P. Nelson,James F. Meschia,Michael A. Nalls,Pankaj Sharma,Andrew B. Singleton,Michel Burnier,John Attia,Maris Laan,Hans L. Hillege,Stefan Kloiber,Hyon K. Choi,Mario Pirastu,Silvia Tore,John Whitfield,Myriam Fornage,Paolo Gasparini,David S. Siscovick,Nabila Bouatia-Naji,Andres Metspalu,Ingrid B. Borecki,Giovanni Gambaro,Ian J. Deary,Bruce H. R. Wolffenbuttel,W. März,Hugh Watkins,Sabine Schipf,Malcolm G. Dunlop,S. Ripatti,Daniela Toniolo,Olli T. Raitakari,Marina Ciullo,Mark J. Caulfield,C Gieger +414 more
TL;DR: A meta-analysis of genome-wide association studies for kidney function–related traits, including 71,149 east Asian individuals from 18 studies in 11 population-, hospital- or family-based cohorts, conducted as part of the Asian Genetic Epidemiology Network (AGEN), identified 17 loci newly associated with kidney function-related traits.
A Comprehensive Evaluation of Potential Lung Function Associated Genes in the SpiroMeta General Population Sample
Ma'en Obeidat,Louise V. Wain,Nick Shrine,Noor Kalsheker,María Soler Artigas,Emmanouela Repapi,Paul Burton,Toby Johnson,Adaikalavan Ramasamy,Jing Hua Zhao,Guangju Zhai,Jennifer E. Huffman,Veronique Vitart,Eva Albrecht,Wilmar Igl,Anna-Liisa Hartikainen,Anneli Pouta,Gemma Cadby,Jennie Hui,Lyle J. Palmer,David Hadley,Wendy L. McArdle,Alicja R. Rudnicka,Inês Barroso,Ruth J. F. Loos,Nicholas J. Wareham,Massimo Mangino,Nicole Soranzo,Tim D. Spector,Sven Glaeser,Georg Homuth,Henry Voelzke,Panos Deloukas,Raquel Granell,John Henderson,Ivica Grković,Stipan Janković,Lina Zgaga,Ozren Polasek,Igor Rudan,Alan F. Wright,Harry Campbell,Sarah H. Wild,James F. Wilson,Joachim Heinrich,Medea Imboden,Nicole Probst-Hensch,Ulf Gyllensten,Åsa Johansson,Ghazal Zaboli,Linda Mustelin,Taina Rantanen,Ida Surakka,Jaakko Kaprio,Marjo-Riitta Järvelin,Caroline Hayward,David M. Evans,Beate Koch,Arthur W. Musk,Paul Elliott,David P. Strachan,Martin D. Tobin,Ian Sayers,Ian P. Hall +63 more
TL;DR: In this article, a meta-analysis of the Genome Wide Association Study (GWAS) results for lung function measures in 20,288 individuals from the general population (the SpiroMeta consortium) was conducted, and the analysis included 16,936 genotyped and imputed SNPs.