D
Daniel Molin
Researcher at Uppsala University
Publications - 100
Citations - 3249
Daniel Molin is an academic researcher from Uppsala University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 25, co-authored 76 publications receiving 2712 citations. Previous affiliations of Daniel Molin include Uppsala University Hospital & Lund University.
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Journal ArticleDOI
Phase II Study of the Efficacy and Safety of Pembrolizumab for Relapsed/Refractory Classic Hodgkin Lymphoma.
Robert W. Chen,Pier Luigi Zinzani,Michelle A. Fanale,Philippe Armand,Nathalie A. Johnson,Pauline Brice,John Radford,Vincent Ribrag,Daniel Molin,Theodoros P. Vassilakopoulos,Akihiro Tomita,Bastian von Tresckow,Margaret A. Shipp,Yinghua Zhang,Alejandro D. Ricart,Arun Balakumaran,Craig H. Moskowitz +16 more
TL;DR: Pembrolizumab was associated with high response rates and an acceptable safety profile in patients with rrHL, offering a new treatment paradigm for this disease.
Journal ArticleDOI
Pembrolizumab in relapsed or refractory Hodgkin lymphoma: 2-year follow-up of KEYNOTE-087
Robert T. Chen,Pier Luigi Zinzani,Hun Ju Lee,Philippe Armand,Nathalie A. Johnson,Pauline Brice,John Radford,Vincent Ribrag,Daniel Molin,Theodoros P. Vassilakopoulos,Akihiro Tomita,Bastian von Tresckow,Margaret A. Shipp,Jianxin Lin,Eunhee Kim,Akash Nahar,Arun Balakumaran,Craig H. Moskowitz +17 more
TL;DR: Results confirmed the effective antitumor activity, durability of response, and manageable safety of pembrolizumab monotherapy in RRcHL, regardless of prior treatment and including chemoresistant cHL.
Journal ArticleDOI
Mast cell infiltration correlates with poor prognosis in Hodgkin's lymphoma
Daniel Molin,Annika Edström,Ingrid Glimelius,Bengt Glimelius,Gunnar Nilsson,Christer Sundström,Gunilla Enblad +6 more
TL;DR: Mast cells were detected in virtually every case and increasing numbers of mast cells correlated to nodular sclerosis histology, and patients with higher mast cell infiltration had a worse relapse‐free survival.
Journal ArticleDOI
A genome-wide association study of Hodgkin's lymphoma identifies new susceptibility loci at 2p16.1 ( REL ), 8q24.21 and 10p14 ( GATA3 )
Victor Enciso-Mora,Peter Broderick,Yussanne Ma,Ruth F. Jarrett,Henrik Hjalgrim,Kari Hemminki,Anke van den Berg,Bianca Olver,Amy Lloyd,Sara E. Dobbins,Tracy Lightfoot,Flora E. van Leeuwen,Asta Försti,Arjan Diepstra,Annegien Broeks,Jayaram Vijayakrishnan,Lesley Shield,Annette Lake,Dorothy Montgomery,Eve Roman,Andreas Engert,Elke Pogge von Strandmann,Katrin S. Reiners,Ilja M. Nolte,Karin E. Smedby,Hans-Olov Adami,Hans-Olov Adami,Nicola S. Russell,Bengt Glimelius,Bengt Glimelius,Stephen Hamilton-Dutoit,Marieke L. De Bruin,Lars P. Ryder,Daniel Molin,Karina Meden Sørensen,Ellen T. Chang,Ellen T. Chang,Malcolm Taylor,Rosie Cooke,Robert M.W. Hofstra,Helga Westers,Tom van Wezel,Ronald van Eijk,Alan Ashworth,Klaus Rostgaard,Mads Melbye,Anthony J. Swerdlow,Richard S. Houlston +47 more
TL;DR: The role of the major histocompatibility complex in disease etiology is confirmed by revealing a strong human leukocyte antigen (HLA) association and new insight is provided into the pathogenesis of cHL.
Journal ArticleDOI
Infectious mononucleosis, childhood social environment, and risk of Hodgkin lymphoma.
Henrik Hjalgrim,Karin E. Smedby,Klaus Rostgaard,Daniel Molin,Stephen Hamilton-Dutoit,Ellen T. Chang,Elisabeth Ralfkiaer,Christer Sundström,Hans-Olov Adami,Bengt Glimelius,Mads Melbye +10 more
TL;DR: The EBV specificity of the IM association was corroborated by a case-case comparison of IM history between younger adult EBV-positive andEBV-negative HL patients, and further evidence was found that IM is associated only with EBv-positive HL, compatible with the notion that EBV - positive and -negative HL may have different etiologies.