D
Dario Presutti
Researcher at Polish Academy of Sciences
Publications - 14
Citations - 281
Dario Presutti is an academic researcher from Polish Academy of Sciences. The author has contributed to research in topics: Medicine & Regenerative medicine. The author has an hindex of 7, co-authored 11 publications receiving 137 citations. Previous affiliations of Dario Presutti include National Research Council.
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Characterization of epithelial-mesenchymal transition intermediate/hybrid phenotypes associated to resistance to EGFR inhibitors in non-small cell lung cancer cell lines
Valentina Fustaino,Dario Presutti,Teresa Colombo,Beatrice Cardinali,Giuliana Papoff,Rossella Brandi,Paola Bertolazzi,Giovanni Felici,Giovina Ruberti +8 more
TL;DR: Interestingly, intermediate/hybrid EMT phenotypes, a collective cell migration and increased stem-like ability associate to resistance to the epidermal growth factor receptor inhibitor, erlotinib, in HCC827 derived cell lines.
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ΔNp63-mediated regulation of hyaluronic acid metabolism and signaling supports HNSCC tumorigenesis
Mirco Compagnone,Veronica Gatti,Dario Presutti,Giovina Ruberti,Claudia Fierro,Elke Markert,Karen H. Vousden,Huiqing Zhou,Alessandro Mauriello,Lucia Anemone,Lucilla Bongiorno-Borbone,Gerry Melino,Gerry Melino,Angelo Peschiaroli +13 more
TL;DR: A ΔNp63-dependent transcriptional program able to regulate the metabolism and the signaling of hyaluronic acid (HA), the major component of the extracellular matrix (ECM), is unveiled and it is found that ∆N p63 is capable of sustaining the production of HA levels in cell culture and in vivo by regulating the expression of the HA synthase HAS3 and two hyaluronidase genes, HYAL-1 andHYAL-3.
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Nanotechnology-Assisted RNA Delivery: From Nucleic Acid Therapeutics to COVID-19 Vaccines.
Chiara Rinoldi,Seyed Shahrooz Zargarian,Paweł Nakielski,Xiaoran Li,Anna Liguori,Francesca Petronella,Dario Presutti,Qiusheng Wang,Marco Costantini,Luciano De Sio,Chiara Gualandi,Bin Ding,Filippo Pierini +12 more
TL;DR: In this paper, a review of the current advances in developing the next generation of drugs based on nanotechnology-assisted RNA delivery is presented, together with the features of the most used RNA molecules and the development strategies and properties of nanostructured vehicles.
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CASP4 gene silencing in epithelial cancer cells leads to impairment of cell migration, cell-matrix adhesion and tissue invasion
Giuliana Papoff,Dario Presutti,Cristiana Lalli,Giulia Bolasco,Simonetta Santini,Candida Manelfi,Valentina Fustaino,Stefano Alemà,Giovina Ruberti +8 more
TL;DR: The data support the emerging evidence that inflammatory caspases can regulate cell migration through actin remodeling and uncover a novel role of CASP4 in cancer cell behavior.
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Recent Advances in Bioprinting Technologies for Engineering Different Cartilage-based Tissues
Tarun Agarwal,Irene Chiesa,Dario Presutti,Vincent Irawan,Kiran Yellappa Vajanthri,Marco Costantini,Yasuhiro Nakagawa,Sheri-Ann Tan,Pooyan Makvandi,Ehsan Nazarzadeh Zare,Esmaeel Sharifi,Carmelo De Maria,Toshiyuki Ikoma,Tapas K. Maiti +13 more
TL;DR: In this article, a review of 3D/4D printing technologies and their implications for the repair of different cartilage tissues, namely, articular, meniscal, nasoseptal, auricular, costal, and tracheal cartilage, is presented.