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David E. Goertz
Researcher at University of Toronto
Publications - 112
Citations - 4190
David E. Goertz is an academic researcher from University of Toronto. The author has contributed to research in topics: Microbubbles & Imaging phantom. The author has an hindex of 33, co-authored 108 publications receiving 3799 citations. Previous affiliations of David E. Goertz include Sunnybrook Health Sciences Centre & Erasmus University Rotterdam.
Papers
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Journal ArticleDOI
In situ conversion of porphyrin microbubbles to nanoparticles for multimodality imaging
Elizabeth Huynh,Ben Y. C. Leung,Brandon Helfield,Mojdeh Shakiba,Julie-Anne Gandier,Cheng S. Jin,Emma R. Master,Brian C. Wilson,David E. Goertz,Gang Zheng +9 more
TL;DR: This work shows the conversion of microbubbles to nanoparticles using low-frequency ultrasound and shows that this conversion is possible in tumour-bearing mice and could be validated using photoacoustic imaging.
Journal ArticleDOI
Attenuation and Size Distribution Measurements of Definity™ and Manipulated Definity™ Populations
TL;DR: It is demonstrated that Definitytrade populations can be manipulated to have improve activity at higher frequencies (>10 MHz), which has implications for UMB and IVUS applications.
Journal ArticleDOI
High frequency nonlinear B-scan imaging of microbubble contrast agents
David E. Goertz,Emmanuel Cherin,Andrew Needles,Raffi Karshafian,A.S. Brown,Peter N. Burns,F.S. Foster +6 more
TL;DR: The development of nonlinear microbubble B-scan imaging instrumentation capable of operating at transmit center frequencies between 10 and 50 MHz and the successful detection of microvessels in the rabbit ear and in the mouse heart is described.
Journal ArticleDOI
Porphyrin Shell Microbubbles with Intrinsic Ultrasound and Photoacoustic Properties
Elizabeth Huynh,Jonathan F. Lovell,Jonathan F. Lovell,Jonathan F. Lovell,Brandon Helfield,Brandon Helfield,Mansik Jeon,Chulhong Kim,David E. Goertz,David E. Goertz,Brian C. Wilson,Brian C. Wilson,Gang Zheng,Gang Zheng +13 more
TL;DR: Porshe MBs were found to be intrinsically suitable for both ultrasound and photoacoustic imaging with a resonance frequency of 9-10 MHz and the porshe stiffness was calculated to be 3-5 times greater than that of commercial lipid MBs.
Journal Article
High-frequency Doppler ultrasound monitors the effects of antivascular therapy on tumor blood flow.
TL;DR: The feasibility of HFD as a noninvasive, quantitative tool for following longitudinally the effects of antivascular therapy on blood flow in superficial tumors is demonstrated.