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David E. Newby
Researcher at University of Edinburgh
Publications - 902
Citations - 45577
David E. Newby is an academic researcher from University of Edinburgh. The author has contributed to research in topics: Myocardial infarction & Coronary artery disease. The author has an hindex of 98, co-authored 805 publications receiving 35865 citations. Previous affiliations of David E. Newby include NHS Lothian & Queen's University.
Papers
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Journal ArticleDOI
Unlocking the Therapeutic Potential of Apelin
Alan G. Japp,David E. Newby +1 more
TL;DR: A comprehensive series of studies are presented that confirm an important role for ACE2 in apelin in the central nervous system and peripheral tissues and identify the most potent and abundant form in cardiac tissue.
Journal ArticleDOI
Left ventricular remodelling and hypertrophy in patients with aortic stenosis: insights from cardiac magnetic resonance imaging
Marc R. Dweck,Sanjiv Joshi,Tim Murigu,Ankur Gulati,Isabelle Roussin,Andrew Jabbour,Winston Banya,Alicia M. Maceira,Francisco Alpendurada,Nicholas A. Boon,Raad H. Mohiaddin,David E. Newby,Dudley J Pennel,Sanjay K Prasad +13 more
TL;DR: This work has sought to investigate the correlation between the severity of aortic stenosis and the hypertrophic response and to define the patterns of remodelling and hypertrophy with CMR.
Proceedings ArticleDOI
LATE-BREAKING ABSTRACT: Study to understand mortality and morbidIty in COPD (SUMMIT)
Jørgen Vestbo,Julie A. Anderson,Robert D. Brook,Peter M.A. Calverley,Bart Celli,Courtney Crim,Fernando J. Martinez,Julie C. Yates,David E. Newby +8 more
TL;DR: Results from the SUMMIT trial should provide important clinical insights into optimal care of patients with mild-moderate COPD who are at-risk for or have CV disease.
Journal ArticleDOI
051 Reducing particulate air pollution exposure in patients with coronary heart disease: improved cardiovascular health
Jeremy P. Langrish,Xia Li,S Wang,M M Y Lee,Gareth Barnes,G L Ge,Mark R. Miller,Flemming R. Cassee,N A Boon,Ken Donaldson,J Li,Nicholas L. Mills,L Jiang,David E. Newby +13 more
TL;DR: In patients with coronary heart disease, wearing a facemask reduces symptoms and is associated with objective improvements in myocardial ischaemia, blood pressure and heart rate variability, this simple well-tolerated intervention has the potential to reduce the incidence of cardiovascular events.
Journal ArticleDOI
Treating aortic stenosis: arresting the snowball effect
Tania Pawade,David E. Newby +1 more
TL;DR: A prospective randomized controlled trial is currently underway for determining whether denosumab or bisphosphonates can slow aortic stenosis disease, which would meet a major unmet clinical need.