D
David E. Newby
Researcher at University of Edinburgh
Publications - 902
Citations - 45577
David E. Newby is an academic researcher from University of Edinburgh. The author has contributed to research in topics: Myocardial infarction & Coronary artery disease. The author has an hindex of 98, co-authored 805 publications receiving 35865 citations. Previous affiliations of David E. Newby include NHS Lothian & Queen's University.
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Journal ArticleDOI
Response to Letter Regarding Article “Diesel Exhaust Inhalation Causes Vascular Dysfunction and Impaired Endogenous Fibrinolysis”
Nicholas L. Mills,Simon D. Robinson,Nicholas A. Boon,David E. Newby,Håkan Törnqvist,Manuel Gonzalez,Anders Blomberg,Thomas Sandström,Kareen Darnley,William MacNee,Ken Donaldson +10 more
TL;DR: At levels encountered in an urban environment, inhalation of dilute diesel exhaust impairs 2 important and complementary aspects of vascular function in humans: the regulation of vascular tone and endogenous fibrinolysis.
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Impaired Coronary Tissue Plasminogen Activator Release Is Associated With Coronary Atherosclerosis and Cigarette Smoking Direct Link Between Endothelial Dysfunction and Atherothrombosis
David E. Newby,Andrew L McLeod,Neal G. Uren,Laura Flint,Christopher A. Ludlam,David J. Webb,Keith A.A. Fox,Nicholas A. Boon +7 more
TL;DR: Findings provide evidence of a direct link between endogenous fibrinolysis, endothelial dysfunction, and atherothrombosis in the coronary circulation and may explain the greater efficacy of thrombolytic therapy for myocardial infarction in cigarette smokers.
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High-sensitivity troponin in the evaluation of patients with suspected acute coronary syndrome: a stepped-wedge, cluster-randomised controlled trial.
Anoop S V Shah,Anoop S V Shah,Atul Anand,Fiona E. Strachan,Amy V. Ferry,Kuan Ken Lee,Andrew R. Chapman,Dennis Sandeman,Catherine L. Stables,Philip D Adamson,Jack P.M. Andrews,Mohamed Anwar,John Hung,A. Moss,Rachel O’Brien,Colin Berry,Iain N Findlay,Simon Walker,Anne Cruickshank,Alan Reid,Alasdair Gray,Paul O. Collinson,Fred S. Apple,David A. McAllister,Donogh Maguire,Keith A.A. Fox,David E. Newby,Chris Tuck,Ronald Harkess,Richard A Parker,Catriona Keerie,Christopher J. Weir,Nicholas L. Mills,Nicholas L. Mills,Lucy Marshall,Stacey Stewart,Takeshi Fujisawa,Catalina A. Vallejos,Athanasios Tsanas,Mischa Hautvast,Jean McPherson,Lynn McKinlay,Jonathan Malo,Colin Fischbacher,Bernard L. Croal,Stephen J Leslie,Allan Walker,Tony Wackett,Roma Armstrong,Laura Stirling,Claire MacDonald,Imran Sadat,Frank Finlay,Heather Charles,Pamela Linksted,Stephen Young,Bill Alexander,Christopher J A Duncan +57 more
TL;DR: The implementation of an hs-cTnI assay was evaluated in consecutive patients who had been admitted to the hospitals' emergency departments with suspected acute coronary syndrome and its findings question whether the diagnostic threshold for myocardial infarction should be based on the 99th centile derived from a normal reference population.
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Long-Term Outcomes in Patients With Type 2 Myocardial Infarction and Myocardial Injury
Andrew R. Chapman,Anoop S V Shah,Kuan Ken Lee,Atul Anand,Oliver Francis,Philip D Adamson,David A. McAllister,Fiona E. Strachan,David E. Newby,Nicholas L. Mills +9 more
TL;DR: It is found that despite an excess in noncardiovascular death, patients with type 2 myocardial infarction or myocardia injury have a similar crude rate of major adverse cardiovascular events as those with type 1Myocardial Infarction.
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Identification of patients and plaques vulnerable to future coronary events with near-infrared spectroscopy intravascular ultrasound imaging: a prospective, cohort study
Ron Waksman,Carlo Di Mario,Rebecca Torguson,Ziad A. Ali,Varinder P. Singh,William H Skinner,Andre Artis,Tim ten Cate,Eric R. Powers,Christopher Kim,Evelyn Regar,S. Chiu Wong,Stephen Alan Lewis,Joanna J. Wykrzykowska,Sandeep Dube,Samer Kazziha,Martin van der Ent,Priti Shah,Paige Craig,Quan Zou,Paul Kolm,H. Bryan Brewer,Hector M. Garcia-Garcia,Habib Samady,Jonathan M. Tobis,Mark Zainea,Wayne Leimbach,Daniel J. Lee,Thomas Lalonde,William Skinner,Augusto E. Villa,Henry A. Liberman,George Younis,Ranil de Silva,Miguel Adrian Diaz,Luis Tami,John McB. Hodgson,Ganesh Raveendran,Nilesh Goswami,José Flores Arias,Lawrence Lovitz,Robert Carida,Srinivasa Potluri,Francesco Prati,Andrejs Erglis,Andrei Pop,Margaret McEntegart,Martin Hudec,Umamahesh C. Rangasetty,David E. Newby +49 more
TL;DR: NIRS imaging of non-obstructive territories in patients undergoing cardiac catheterisation and possible percutaneous coronary intervention was safe and can aid in identifying patients and segments at higher risk for subsequent NC-MACE.