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David E. Newby

Researcher at University of Edinburgh

Publications -  902
Citations -  45577

David E. Newby is an academic researcher from University of Edinburgh. The author has contributed to research in topics: Myocardial infarction & Coronary artery disease. The author has an hindex of 98, co-authored 805 publications receiving 35865 citations. Previous affiliations of David E. Newby include NHS Lothian & Queen's University.

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Response to Letter Regarding Article “Diesel Exhaust Inhalation Causes Vascular Dysfunction and Impaired Endogenous Fibrinolysis”

TL;DR: At levels encountered in an urban environment, inhalation of dilute diesel exhaust impairs 2 important and complementary aspects of vascular function in humans: the regulation of vascular tone and endogenous fibrinolysis.
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Impaired Coronary Tissue Plasminogen Activator Release Is Associated With Coronary Atherosclerosis and Cigarette Smoking Direct Link Between Endothelial Dysfunction and Atherothrombosis

TL;DR: Findings provide evidence of a direct link between endogenous fibrinolysis, endothelial dysfunction, and atherothrombosis in the coronary circulation and may explain the greater efficacy of thrombolytic therapy for myocardial infarction in cigarette smokers.
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High-sensitivity troponin in the evaluation of patients with suspected acute coronary syndrome: a stepped-wedge, cluster-randomised controlled trial.

TL;DR: The implementation of an hs-cTnI assay was evaluated in consecutive patients who had been admitted to the hospitals' emergency departments with suspected acute coronary syndrome and its findings question whether the diagnostic threshold for myocardial infarction should be based on the 99th centile derived from a normal reference population.
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Long-Term Outcomes in Patients With Type 2 Myocardial Infarction and Myocardial Injury

TL;DR: It is found that despite an excess in noncardiovascular death, patients with type 2 myocardial infarction or myocardia injury have a similar crude rate of major adverse cardiovascular events as those with type 1Myocardial Infarction.
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Identification of patients and plaques vulnerable to future coronary events with near-infrared spectroscopy intravascular ultrasound imaging: a prospective, cohort study

TL;DR: NIRS imaging of non-obstructive territories in patients undergoing cardiac catheterisation and possible percutaneous coronary intervention was safe and can aid in identifying patients and segments at higher risk for subsequent NC-MACE.