D
David E. Newby
Researcher at University of Edinburgh
Publications - 902
Citations - 45577
David E. Newby is an academic researcher from University of Edinburgh. The author has contributed to research in topics: Myocardial infarction & Coronary artery disease. The author has an hindex of 98, co-authored 805 publications receiving 35865 citations. Previous affiliations of David E. Newby include NHS Lothian & Queen's University.
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Journal ArticleDOI
Deep learning-enabled coronary CT angiography for plaque and stenosis quantification and cardiac risk prediction: an international multicentre study
Andrew Li,Nipun Manral,Priscilla McElhinney,Aditya Killekar,Hidenari Matsumoto,Jacek Kwiecinski,Konrad Pieszko,Aryabod Razipour,Kajetan Grodecki,Caroline Park,Yuka Otaki,Mhairi K. Doris,Alan C. Kwan,Donghee Han,Keiichiro Kuronuma,Guadalupe Flores Tomasino,Evangelos Tzolos,Aakash Shanbhag,Markus Goeller,Mohamed Marwan,Heidi Gransar,Balaji Tamarappoo,Sebastien Cadet,Stephan Achenbach,Stephen J. Nicholls,Dennis T.L. Wong,Daniel S. Berman,Marc R. Dweck,David E. Newby,Michelle A. Williams,Piotr J. Slomka,Damini Dey +31 more
TL;DR: The authors' novel, externally validated deep learning system provides rapid measurements of plaque volume and stenosis severity from CCTA that agree closely with expert readers and intravascular ultrasound, and could have prognostic value for future myocardial infarction.
Journal ArticleDOI
Machine-learning with 18F-sodium fluoride PET and quantitative plaque analysis on CT angiography for the future risk of myocardial infarction.
Jacek Kwiecinski,Evangelos Tzolos,Mohammed N. Meah,Sebastien Cadet,Philip D Adamson,Kajetan Grodecki,Nikhil Joshi,Alastair J Moss,Michelle C. Williams,Edwin J R van Beek,Daniel S. Berman,David E. Newby,Damini Dey,Marc R. Dweck,Piotr J. Slomka +14 more
TL;DR: In this article, an optimal machine-learning model for the future risk of myocardial infarction in patients with stable coronary disease was developed by combining clinical data with these approaches in a machine learning model.
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Pneumonia risk with inhaled fluticasone furoate and vilanterol in COPD patients with moderate airflow limitation: The SUMMIT trial
Courtney Crim,Peter M.A. Calverley,Julie A. Anderson,Andrew P. Holmes,Sally Kilbride,Fernando J. Martinez,Robert D. Brook,David E. Newby,Julie C. Yates,Bartolome R. Celli,Jørgen Vestbo,Summit investigators +11 more
TL;DR: In contrast to previous studies in patients with severe disease, increased pneumonia risk with inhaled corticosteroid use was not evident in COPD subjects with moderate airflow limitation and heightened cardiovascular risk.
Journal ArticleDOI
Low serum cortisol predicts early death after acute myocardial infarction.
Rebecca M. Reynolds,Brian R. Walker,Sally Haw,David E. Newby,Daniel F. Mackay,Stuart M. Cobbe,Alastair C H Pell,Colin Fischbacher,Stuart D. Pringle,David Murdoch,F G Dunn,Keith G. Oldroyd,Paul D MacIntyre,Brian O’Rourke,Jill P. Pell +14 more
TL;DR: Patients who mount a lesser cortisol stress response to acute myocardial infarction have a poorer early prognosis than those who survived and are a strong predictor of death within 30 days.
Journal ArticleDOI
FEV 1 is a stronger mortality predictor than FVC in patients with moderate COPD and with an increased risk for cardiovascular disease
Andras Bikov,Andras Bikov,Peter Lange,Peter Lange,Julie A. Anderson,Robert D. Brook,Peter M.A. Calverley,Bartolome R. Celli,Nicholas J. Cowans,Courtney Crim,Ian J. Dixon,Fernando J. Martinez,David E. Newby,Julie C. Yates,Jørgen Vestbo,Jørgen Vestbo +15 more
TL;DR: It is suggested that FEV1 is a stronger predictor for all-cause mortality than FVC inmoderate COPD patients with heightened cardiovascular risk and that subjects with moderate COPD have very different risks.