D
David Heber
Researcher at University of California, Los Angeles
Publications - 445
Citations - 32045
David Heber is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Cancer & Medicine. The author has an hindex of 90, co-authored 393 publications receiving 29672 citations. Previous affiliations of David Heber include Oklahoma State University Center for Health Sciences & University of California, Berkeley.
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Journal ArticleDOI
In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagic acid and a total pomegranate tannin extract are enhanced in combination with other polyphenols as found in pomegranate juice
Navindra P. Seeram,Lynn S. Adams,Susanne M. Henning,Yantao Niu,Yanjun Zhang,Muraleedharan G. Nair,David Heber +6 more
TL;DR: The superior bioactivity of PJ compared to its purified polyphenols illustrated the multifactorial effects and chemical synergy of the action of multiple compounds compared to single purified active ingredients.
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Low-fat dietary pattern and risk of cardiovascular disease : The women's health initiative randomized controlled dietary modification trial
Barbara V. Howard,Barbara V. Howard,Linda Van Horn,Judith Hsia,JoAnn E. Manson,Marcia L. Stefanick,Sylvia Wassertheil-Smoller,Lewis H. Kuller,Andrea Z. LaCroix,Robert Langer,Norman L. Lasser,Cora E. Lewis,Marian C. Limacher,Karen L. Margolis,W. Jerry Mysiw,Judith K. Ockene,Linda M. Parker,Michael G. Perri,Lawrence S. Phillips,Ross L. Prentice,John A Robbins,Jacques E. Rossouw,Gloria E. Sarto,Irwin J. Schatz,Linda Snetselaar,Victor J. Stevens,Lesley F. Tinker,Maurizio Trevisan,Mara Z. Vitolins,Garnet L. Anderson,Annlouise R. Assaf,Annlouise R. Assaf,Tamsen Bassford,Shirley A.A. Beresford,Henry R. Black,Robert L. Brunner,Robert G. Brzyski,Bette J. Caan,Rowan T. Chlebowski,Margery Gass,Iris A. Granek,Philip Greenland,Jennifer Hays,David Heber,Gerardo Heiss,Susan L. Hendrix,F. Allan Hubbell,Karen C. Johnson,Jane Morley Kotchen +48 more
TL;DR: A dietary intervention that reduced total fat intake and increased intakes of vegetables, fruits, and grains did not significantly reduce the risk of CHD, stroke, or CVD in postmenopausal women and achieved only modest effects on CVD risk factors, suggesting that more focused diet and lifestyle interventions may be needed to improve risk factors and reduce CVDrisk.
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Weight Control and Risk Factor Reduction in Obese Subjects Treated for 2 Years With Orlistat: A Randomized Controlled Trial
Michael H. Davidson,Jonathan Hauptman,Mario DiGirolamo,John P. Foreyt,Charles H. Halsted,David Heber,Douglas C. Heimburger,Charles P. Lucas,David C. Robbins,Jain Chung,Steven B. Heymsfield +10 more
TL;DR: Two-year treatment with orlistat plus diet significantly promotes weight loss, lessens weight regain, and improves some obesity-related disease risk factors.
Journal ArticleDOI
Ligands for peroxisome proliferator-activated receptorgamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice.
E Elstner,Claudia I. Muller,K Koshizuka,Elizabeth A. Williamson,Dorothy J. Park,H Asou,P Shintaku,Jonathan W. Said,David Heber,H P Koeffler +9 more
TL;DR: The combination of TGZ and ATRA synergistically and irreversibly inhibits growth and induces apoptosis of MCF7 breast cancer cells and the combination may provide a novel, nontoxic and selective therapy for human breast cancers.
Journal ArticleDOI
Blackberry, black raspberry, blueberry, cranberry, red raspberry, and strawberry extracts inhibit growth and stimulate apoptosis of human cancer cells in vitro.
Navindra P. Seeram,Lynn S. Adams,Yanjun Zhang,Ru-Po Lee,Daniel Sand,Henry S Scheuller,David Heber +6 more
TL;DR: The data provided by the current study and from other laboratories warrants further investigation into the chemopreventive and chemotherapeutic effects of berries using in vivo models.