David Spiegel

TL;DR: In this paper, the authors provide updated information on psychotherapeutic interventions geared towards cancer patients suffering from depressive disorders, and its impact on disease progression, including depression associated with impaired immune response and poorer survival in patients with cancer.

TL;DR: Efficient, multigram-scale syntheses of all MG-H-amino acid building blocks are developed, suitably protected for solid-phase peptide synthesis, in 2-3 steps starting from inexpensive, readily available starting materials, and expect the synthetic reagents reported herein to enable investigations into non-enzymatic protein regulation at an unprecedented level of detail.

TL;DR: The ubiquitous glyoxalase enzymatic pathway is involved in the detoxification of methylglyoxal (MG), a cytotoxic byproduct of glycolysis, and has been shown to be important for pollination responses.

TL;DR: Family environment was a better predictor of rehospitalization than baseline ratings of clinical status, indicating the importance of family support in the community adjustment of chronic psychiatric patients.

TL;DR: Subjective sleep problems are associated with poor clinical outcomes in metastatic colorectal cancer patients and affect chronotherapy effectiveness, and there is a need for a well-tuned circadian timing system in order to increase chronotherapy activity.