D
Derrick W. Crook
Researcher at University of Oxford
Publications - 510
Citations - 38699
Derrick W. Crook is an academic researcher from University of Oxford. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 92, co-authored 474 publications receiving 29885 citations. Previous affiliations of Derrick W. Crook include Oxford Brookes University & The Chinese University of Hong Kong.
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TETyper: a bioinformatic pipeline for classifying variation and genetic contexts of transposable elements from short-read whole-genome sequencing data
Anna E. Sheppard,Nicole Stoesser,Ian German-Mesner,Kasi Vegesana,A. Sarah Walker,Derrick W. Crook,Amy J. Mathers +6 more
TL;DR: TETyper takes short-read whole-genome sequencing data as input and identifies single-nucleotide mutations and deletions within the TE of interest, to enable tracking of specific sequence variants, as well as the surrounding genetic context(s), to enable identification of transposition events.
Journal ArticleDOI
Capsular Type and the Pneumococcal Human Host-Parasite Relationship
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Human and Porcine Transmission of Clostridioides difficile Ribotype 078, Europe.
G Moloney,David W Eyre,M M Aogáin,M C McElroy,Alison Vaughan,Peto Tea.,Derrick W. Crook,T R Rogers +7 more
TL;DR: Genomic analysis of a diverse collection of Clostridioides difficile ribotype 078 isolates from Ireland and 9 countries in Europe provided evidence for complex regional and international patterns of dissemination that are not restricted to humans as mentioned in this paper.
Journal ArticleDOI
Cross-reaction of spontaneous capsule-deficient Haemophilus influenzae type b mutants with type-specific antisera.
TL;DR: 1. Chernesky MA, Delong D J, Mahony JB, Castriciano S: Differences in antibody responses with rapid agglutination tests for the detection of rubella antibodies.
Journal ArticleDOI
Comparative genomics of Clostridioides difficile toxinotypes identifies module-based toxin gene evolution.
Sandra Janezic,Kate E. Dingle,Joseph W. Alvin,Tomaž Accetto,Xavier Didelot,Derrick W. Crook,D. Borden Lacy,D. Borden Lacy,Maja Rupnik +8 more
TL;DR: Analysis of a comprehensive collection of all known major C. difficile toxinotypes to address the evolutionary relationships of the toxin gene variants, the mechanisms underlying the origin and development of variability in toxin genes and the PaLoc, and the relationship between structure and function in TcdB variants.