D
Derrick W. Crook
Researcher at University of Oxford
Publications - 510
Citations - 38699
Derrick W. Crook is an academic researcher from University of Oxford. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 92, co-authored 474 publications receiving 29885 citations. Previous affiliations of Derrick W. Crook include Oxford Brookes University & The Chinese University of Hong Kong.
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Journal ArticleDOI
Renal impairment and clinical outcomes of Clostridium difficile infection in two randomized trials.
Kathleen M. Mullane,Oliver A. Cornely,Derrick W. Crook,Yoav Golan,Thomas J. Louie,Mark A. Miller,Michelle A. Josephson,Sherwood L. Gorbach +7 more
TL;DR: Progressive CKD is associated with increased TTROD, lower cure rates, and higher recurrence rates with treatment of CDI, and the rate of recurrence was higher following vancomycin treatment independent of renal function.
Journal ArticleDOI
Antibody persistence and Haemophilus influenzae type b carriage after infant immunisation with PRP-T
Paul T. Heath,J Bowen-Morris,David J. Griffiths,Helen Griffiths,Derrick W. Crook,E. R. Moxon +5 more
TL;DR: In this paper, the persistence of serum Haemophilus influenzae type b antibodies and the prevalence of H influenzAE type b carriage in a group of preschool age children previously vaccinated in infancy were assessed.
Proceedings ArticleDOI
Machine learning for the prediction of antibacterial susceptibility in Mycobacterium tuberculosis
TL;DR: A machine-learning approach for predicting bacterial susceptibility from genomic data using the presence or absence of over 500 single nucleotide polymorphisms found in a dataset of 652 bacterial isolates from the Oxford University Hospitals NHS Trust and elsewhere in the UK was described.
Journal ArticleDOI
Comparison of Control of Clostridium difficile Infection in Six English Hospitals Using Whole-Genome Sequencing.
David W Eyre,W. N. Fawley,A Rajgopal,Chris D Settle,K Mortimer,Simon D. Goldenberg,S Dawson,Derrick W. Crook,Peto Tea.,Anne-Sophie Walker,Mark H. Wilcox +10 more
TL;DR: Infection control effectiveness at 6 English hospitals was compared using whole-genome sequencing of C. difficile isolates to suggest transmission from a previous isolate, with results ranging from 7% at the best institution to 22% in most others.
Journal ArticleDOI
NFKBIZ polymorphisms and susceptibility to pneumococcal disease in European and African populations
Stephen J Chapman,Chiea Chuen Khor,Chiea Chuen Khor,Fredrik O. Vannberg,Anna Rautanen,Shelley Segal,Catrin E. Moore,Davies Rjo.,N P Day,N Peshu,Derrick W. Crook,James A. Berkley,Thomas N. Williams,J A Scott,Hill Avs. +14 more
TL;DR: It is concluded that multiple NFKBIZ polymorphisms associate with susceptibility to IPD in humans and the study of multiple populations may aid in fine mapping of associations within extensive regions of strong LD (‘transethnic mapping’).