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Derrick W. Crook
Researcher at University of Oxford
Publications - Â 510
Citations - Â 38699
Derrick W. Crook is an academic researcher from University of Oxford. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 92, co-authored 474 publications receiving 29885 citations. Previous affiliations of Derrick W. Crook include Oxford Brookes University & The Chinese University of Hong Kong.
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Quantitative SARS-CoV-2 anti-spike responses to Pfizer-BioNTech and Oxford-AstraZeneca vaccines by previous infection status.
DW Eyre,S F Lumley,Jia Wei,Stuart Cox,Tim James,Anita Justice,Gerald Jesuthasan,Denise O'Donnell,Alison Howarth,Stephanie B Hatch,Brian D. Marsden,E Y Jones,David I. Stuart,Daniel Ebner,Sarah Hoosdally,Derrick W. Crook,T Peto,Timothy M Walker,Nicole Stoesser,Philippa C Matthews,Koen B. Pouwels,Anne-Sophie Walker,Anne-Sophie Walker,Katie Jeffery +23 more
TL;DR: In this paper, the determinants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) anti-spike IgG responses in healthcare workers (HCWs) following one or two doses of Pfizer-BioNTech or Oxford-AstraZeneca vaccines were investigated.
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Sequence and functional analyses of Haemophilus spp. genomic islands
Mario Juhas,Peter M. Power,Rosalind M. Harding,David J. P. Ferguson,Ioanna D. Dimopoulou,Abdel R E Elamin,Zaini Mohd-Zain,Derek W. Hood,Richard A. Adegbola,Alice L. Erwin,Arnold L. Smith,Robert S. Munson,Alistair Harrison,Lucielle Mansfield,Stephen D. Bentley,Derrick W. Crook +15 more
TL;DR: Comparison of conjugation efficiency and antibiotic susceptibility demonstrates that phenotypic expression of genomic island-borne genes differs between different hosts, as well as the co-evolving as semi-autonomous genomes within the 'supragenomes' of their host species.
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Genomic epidemiology of global Klebsiella pneumoniae carbapenemase (KPC)-producing Escherichia coli.
Nicole Stoesser,Anna E. Sheppard,Gisele Peirano,LW Anson,Louise Pankhurst,Robert Sebra,H T T Phan,H T T Phan,Andrew Kasarskis,Amy J. Mathers,Tim E. A. Peto,Patricia A. Bradford,Mary Motyl,A S Walker,Derrick W. Crook,Johann D. D. Pitout +15 more
TL;DR: The association of blaKPC with a range of MGEs previously linked to the successful spread of widely endemic resistance mechanisms suggests that it may become similarly prevalent, and evidence of inter-species, regional and international plasmid spread is found.
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Severe infections emerge from commensal bacteria by adaptive evolution
Bernadette C. Young,Chieh-Hsi Wu,N. Claire Gordon,Kevin Cole,James Price,James Price,Elian Liu,Anna E. Sheppard,Anna E. Sheppard,Srinath Perera,Jane Charlesworth,Tanya Golubchik,Zamin Iqbal,Rory Bowden,Ruth C. Massey,John Paul,John Paul,Derrick W. Crook,Derrick W. Crook,Derrick W. Crook,Tim E. A. Peto,Tim E. A. Peto,A. Sarah Walker,A. Sarah Walker,Martin J. Llewelyn,Martin J. Llewelyn,David H. Wyllie,Daniel J. Wilson,Daniel J. Wilson +28 more
TL;DR: It is reported that 72% of infections emerged from the nose, with infecting and nose-colonizing bacteria showing parallel adaptive differences, suggesting infection-associated, short-term, within-host selection pressures.
Journal ArticleDOI
Characterization of Genetic and Phenotypic Diversity of Invasive Nontypeable Haemophilus influenzae
Alice L. Erwin,Kevin L. Nelson,Tendai Mhlanga-Mutangadura,Paul J. Bonthuis,Jennifer L. Geelhood,Gregory Morlin,William C. T. Unrath,José Campos,Derrick W. Crook,Monica M. Farley,Frederick W. Henderson,Richard F. Jacobs,Kathrin Mühlemann,Sarah W. Satola,Loek van Alphen,Miriam Golomb,Arnold L. Smith +16 more
TL;DR: It is concluded that invasive isolates are genetically and phenotypically diverse and that certain genetic loci of NTHi are frequently found in association among Nthi strains.