D
Derrick W. Crook
Researcher at University of Oxford
Publications - 510
Citations - 38699
Derrick W. Crook is an academic researcher from University of Oxford. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 92, co-authored 474 publications receiving 29885 citations. Previous affiliations of Derrick W. Crook include Oxford Brookes University & The Chinese University of Hong Kong.
Papers
More filters
Journal ArticleDOI
Antibody responses and correlates of protection in the general population after two doses of the ChAdOx1 or BNT162b2 vaccines
Jia-mei Wei,Koen B. Pouwels,Nicole Stoesser,Philippa C Matthews,Ian Diamond,Ruth Studley,Emma Rourke,D. Cook,John I. Bell,John N Newton,Jeremy Farrar,Alison Howarth,Brian D. Marsden,Sarah Hoosdally,E Y Jones,David I. Stuart,Derrick W. Crook,Tim E. A. Peto,A. Sarah Walker,David W Eyre,Tina Thomas,Daniel Ayoubkhani,Russell C. Black,Anton Felton,M.J. Crees,Joel Jones,L. Lloyd,Esther Sutherland,Emma Pritchard,Karina-Doris Vihta,George Doherty,James Kavanagh,Kevin K Chau,Stephanie B Hatch,Daniel Ebner,Lucas Martins Ferreira,Thomas Christott,Wanwisa Dejnirattisai,Juthathip Mongkolsapaya,Sarah Cameron,Phoebe Tamblin-Hopper,Magda Wolna,Rachael Brown,Richard J. Cornall,Gavin R. Screaton,Katrina A. Lythgoe,David Bonsall,Tanya Golubchik,Helen R. Fryer,Stuart Cox,K Paddon,Tim James,Thomas M. Boyd Jason R. House,Julie V. Robotham,Paul J Birrell,H. Jordan,Tim Sheppard,Graham Athey,Daniel S. Moody,Leigh Curry,P. J. Brereton,Ian Jarvis,Anna Godsmark,George Morris,Bobby Mallick,Phil Eeles,Jodie Hay,Harper C VanSteenhouse,Jessica Lee,Sean A. White,Tim S. Evans,Lisa Bloemberg,Katie Allison,Anouska Pandya,Sophie Frances Davis,David I. Conway,Margaret MacLeod,Chris Cunningham +77 more
TL;DR: In this article , the authors investigated anti-spike IgG antibody responses and correlates of protection after second doses of ChAdOx1 or BNT162b2 vaccines for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Journal ArticleDOI
Mortality risks associated with emergency admissions during weekends and public holidays: an analysis of electronic health records
A. Sarah Walker,Amy M. Mason,T Phuong Quan,N J Fawcett,Peter J. Watkinson,Martin J. Llewelyn,Martin J. Llewelyn,Nicole Stoesser,John Finney,Jim Davies,Jim Davies,David H. Wyllie,David H. Wyllie,Derrick W. Crook,Tim E. A. Peto +14 more
TL;DR: The findings suggest that the weekend effect arises from patient-level differences at admission rather than reduced hospital staffing or services, and adjustment for routine test results substantially reduced excess mortality associated with emergency admission at weekends and public holidays.
Journal ArticleDOI
Pneumococcal genome sequencing tracks a vaccine escape variant formed through a multi-fragment recombination event.
Tanya Golubchik,Angela B. Brueggemann,Teresa L Street,Robert E. Gertz,Chris C. A. Spencer,Thien Anh Ho,Eleni Giannoulatou,Ruth Link-Gelles,Rosalind M. Harding,Bernard Beall,Tim E. A. Peto,Matthew R. Moore,Peter Donnelly,Peter Donnelly,Derrick W. Crook,Rory Bowden,Rory Bowden +16 more
TL;DR: It is shown that one such new strain quickly became established, spreading from east to west across the United States, and provides proof of principle of the considerable value of combining genomic and epidemiological information in the surveillance and enhanced understanding of infectious diseases.
Journal ArticleDOI
Metagenomic Nanopore sequencing of influenza virus direct from clinical respiratory samples
Kuiama Lewandowski,Yifei Xu,Steven T. Pullan,Sheila F Lumley,Dona Foster,Nicholas D Sanderson,Alison Vaughan,Marcus Morgan,Nicole Bright,James Kavanagh,Richard Vipond,Miles W. Carroll,Anthony C. Marriott,Karen E. Gooch,Monique Andersson,Katie Jeffery,Tim E. A. Peto,Derrick W. Crook,A. Sarah Walker,Philippa C Matthews,Philippa C Matthews +20 more
TL;DR: While further optimization is required to improve sensitivity, this approach shows promise for the Nanopore platform to be used in the diagnosis and genetic analysis of influenza virus and other respiratory viruses.
Journal ArticleDOI
Trends over time in Escherichia coli bloodstream infections, urinary tract infections, and antibiotic susceptibilities in Oxfordshire, UK, 1998-2016: a study of electronic health records.
Karina-Doris Vihta,Karina-Doris Vihta,Nicole Stoesser,Martin J. Llewelyn,T Phuong Quan,T Phuong Quan,Tim Davies,Tim Davies,Nicola J Fawcett,Laura Dunn,Katie Jeffery,Christopher C Butler,Gail Hayward,Monique Andersson,Marcus Morgan,Sarah Oakley,Amy M. Mason,Susan Hopkins,David H. Wyllie,Derrick W. Crook,Derrick W. Crook,Derrick W. Crook,Mark H. Wilcox,Alan P. Johnson,Alan P. Johnson,Tim E. A. Peto,Tim E. A. Peto,A. Sarah Walker,A. Sarah Walker +28 more
TL;DR: Increases in E coli bloodstream infections in Oxfordshire are primarily community associated, with substantial co-amoxiclav resistance; nevertheless, there is little or no change in mortality.