Diane S. Krause

TL;DR: It is observed that the predicted targets of predicted target mRNAs are significantly anti-correlated with the variation of abundantly expressed miRNAs, suggesting that miRNA expression variability alone may lead to non-genetic cell-to-cell heterogeneity.

TL;DR: A unique genetic profile is presented that includes bi‐allelic deletions within 13q14, where the retinoblastoma tumor suppressor gene (RB1) resides, as well as isolated trisomy 21 without a concomitant mutation in the hematopoietic transcription factor GATA1s and translocation that does not involve the megakaryoblastic leukemia 1 (MKL1) gene located on chromosome 22.

TL;DR: Discovery of a cofactor for GATA-1 opens new avenues of investigation into the transcriptional regulation of hematopoiesis.

TL;DR: It is shown for the first time that MS can be prevented if BMT is performed before disease onset as assessed by improved lifespan, renal function, renal histology, and TEM analysis.

TL;DR: It is concluded that collection of HPC using hyperstimulation with G‐CSF is an effective alternative approach for HPC harvest for poorly mobilized patients.