D
Donald E. Low
Researcher at University of Toronto
Publications - 362
Citations - 25624
Donald E. Low is an academic researcher from University of Toronto. The author has contributed to research in topics: Population & Streptococcus pneumoniae. The author has an hindex of 88, co-authored 359 publications receiving 24384 citations. Previous affiliations of Donald E. Low include Trillium Health Centre & New York City Department of Health and Mental Hygiene.
Papers
More filters
Journal ArticleDOI
Identification of Severe Acute Respiratory Syndrome in Canada
Susan M. Poutanen,Susan M. Poutanen,Donald E. Low,Bonnie Henry,Sandy Finkelstein,David Rose,Karen Green,Raymond Tellier,Raymond Tellier,Ryan Draker,Dena Adachi,Melissa Ayers,Adrienne K. Chan,Danuta M. Skowronski,Irving E. Salit,Andrew E. Simor,Arthur S. Slutsky,Patrick Doyle,Mel Krajden,Martin Petric,Robert C. Brunham,Allison McGeer +21 more
TL;DR: SARS appears to be of viral origin, with patterns suggesting droplet or contact transmission, and the role of human metapneumovirus, a novel coronavirus, or both requires further investigation.
Journal ArticleDOI
Intravenous Immunoglobulin Therapy for Streptococcal Toxic Shock Syndrome—A Comparative Observational Study
Rupert Kaul,Allison McGeer,Anna Norrby-Teglund,Malak Kotb,Benjamin Schwartz,Keith O'Rourke,James Talbot,Donald E. Low +7 more
TL;DR: IVIG therapy enhanced the ability of patient plasma to neutralize bacterial mitogenicity and reduced T cell production of interleukin-6 and tumor necrosis factor alpha and may be an effective adjunctive therapy for streptococcal TSS.
Journal ArticleDOI
Resistance to Levofloxacin and Failure of Treatment of Pneumococcal Pneumonia
Ross J Davidson,Rodrigo B. Cavalcanti,James L. Brunton,Darrin J. Bast,Joyce C. S. de Azavedo,Pamela Kibsey,Christine Fleming,Donald E. Low +7 more
TL;DR: In these patients, the isolates of Streptococcus pneumoniae were resistant to levofloxacin, and in two of them the resistance appeared to have been acquired during the current course of treatment with fluoroquinolones.
Journal ArticleDOI
Population-Based Surveillance for Group A Streptococcal Necrotizing Fasciitis: Clinical Features, Prognostic Indicators, and Microbiologic Analysis of Seventy-Seven Cases
TL;DR: The incidence of necrotizing fasciitis caused by group A streptococcus increased in Ontario between 1992 and 1995 and was associated with the presence of hypotension, Strep TSS, or bacteremia, but not with M-type or the absence of pyrogenic exotoxin genes.
Journal ArticleDOI
Evidence for a Clonal Origin of Methicillin Resistance in Staphylococcus aureus
Barry N. Kreiswirth,John Kornblum,John Kornblum,Robert D. Arbeit,William Eisner,Joel N. Maslow,Allison McGeer,Donald E. Low,Richard P. Novick +8 more
TL;DR: An investigation of the clonality of 472 isolates by DNA hybridization was performed, suggesting that mecA divergence preceded the acquisition of Tn554 in all cases and therefore thatmecA may have been acquired just once by S. aureus.