D
Donna G. Blackmond
Researcher at Scripps Health
Publications - 218
Citations - 13584
Donna G. Blackmond is an academic researcher from Scripps Health. The author has contributed to research in topics: Catalysis & Homochirality. The author has an hindex of 62, co-authored 210 publications receiving 12046 citations. Previous affiliations of Donna G. Blackmond include Scripps Research Institute & Max Planck Society.
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Journal ArticleDOI
Energy threshold for chiral symmetry breaking in molecular self-replication.
TL;DR: The magnitude of the energy imbalance required to induce directed symmetry breaking and asymmetric amplification in the Soai reaction has now been identified and compared to the parity violation energy difference.
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Kinetic correlation between aldehyde/enamine stereoisomers in reactions between aldehydes with α-stereocenters and chiral pyrrolidine-based catalysts
TL;DR: In this article, the formation of enamines between aldehydes with α-stereocenters and pyrrolidine-based catalysts that lack an acidic proton is examined by kinetic and spectroscopic studies.
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A Coherent Mechanistic Rationale for Additive Effects and Autoinductive Behaviour in Proline-Mediated Reactions
TL;DR: Differences in the kinetic behaviour of aldol reactions compared to aminoxylation and amination reactions are rationalized by consideration of the rate-d determining step in each case.
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A Role for Pd(IV) in Catalytic Enantioselective C–H Functionalization with Monoprotected Amino Acid Ligands under Mild Conditions
R. Erik Plata,David E. Hill,Brandon E. Haines,Djamaladdin G. Musaev,Ling Chu,David P. Hickey,Matthew S. Sigman,Jin-Quan Yu,Donna G. Blackmond +8 more
TL;DR: Electrochemical experiments demonstrate the viability of oxidative addition of I2 to Pd(II), and observations suggest that iodine oxidizes Pd prior to addition of the amine substrate, which may lead to a better general understanding of the subtle variations in the reaction mechanisms for C-H functionalization reactions.
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Asymmetric Hydrogenation of Ethyl Pyruvate: Diffusion Effects on Enantioselectivity
TL;DR: In this paper, the authors observed a change in the observed kinetics from the zero-order substrate dependence typical of gas-liquid diffusion control to a positive dependence on substrate concentration, even for a series of reactions carried out at constant pressure.