D
Donna G. Blackmond
Researcher at Scripps Health
Publications - 218
Citations - 13584
Donna G. Blackmond is an academic researcher from Scripps Health. The author has contributed to research in topics: Catalysis & Homochirality. The author has an hindex of 62, co-authored 210 publications receiving 12046 citations. Previous affiliations of Donna G. Blackmond include Scripps Research Institute & Max Planck Society.
Papers
More filters
Journal ArticleDOI
Amplification of Enantiomeric Excess in a Proline-Mediated Reaction†
Journal ArticleDOI
A re-examination of pressure effects on enantioselectivity in asymmetric catalytic hydrogenation
TL;DR: In this paper, it was shown that the reported pressure dependence on enantioselectivity may in fact be reproduced at constant pressure for several systems by varying the rate of gas−liquid mass transfer.
Journal ArticleDOI
On the Origin of Single Chirality of Amino Acids and Sugars in Biogenesis
Jason E. Hein,Donna G. Blackmond +1 more
TL;DR: This work incorporates both chemical and physical phenomena that allow for the amplification of a small initial imbalance of either sugars by amino acids or amino acid by sugars, suggesting that an enantioenriched chiral pool of one type of molecule could lead to a similarly enantIOenriched pool of the other.
Journal ArticleDOI
Potassium tert-Butoxide-Catalyzed Dehydrogenative C-H Silylation of Heteroaromatics: A Combined Experimental and Computational Mechanistic Study.
Wen-Bo Liu,David P. Schuman,Yun-Fang Yang,Anton A. Toutov,Yong Liang,Hendrik F. T. Klare,Nasri Nesnas,Martin Oestreich,Donna G. Blackmond,Scott C. Virgil,Shibdas Banerjee,Richard N. Zare,Robert H. Grubbs,Kendall N. Houk,Brian M. Stoltz +14 more
TL;DR: A systematic experimental and computational mechanistic investigation of the direct dehydrogenative C-H silylation of heteroaromatics utilizing Earth-abundant potassium tert-butoxide shows that H2 is formed by a cross-dehydrogenative mechanism.
Journal ArticleDOI
Mechanistic rationalization of organocatalyzed conjugate addition of linear aldehydes to nitro-olefins
TL;DR: Kinetic studies of the conjugate addition of propanal to nitrostyrene catalyzed by diarylprolinol ethers reveal that formation of the product iminium species is rate-determining and is promoted by both the reaction product and acid additives.