D
Donna G. Blackmond
Researcher at Scripps Health
Publications - 218
Citations - 13584
Donna G. Blackmond is an academic researcher from Scripps Health. The author has contributed to research in topics: Catalysis & Homochirality. The author has an hindex of 62, co-authored 210 publications receiving 12046 citations. Previous affiliations of Donna G. Blackmond include Scripps Research Institute & Max Planck Society.
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Journal ArticleDOI
Pasteur's tweezers revisited: on the mechanism of attrition-enhanced deracemization and resolution of chiral conglomerate solids.
Jason E. Hein,Jason E. Hein,Blessing Huynh Cao,Cristobal Viedma,Richard M. Kellogg,Donna G. Blackmond +5 more
TL;DR: Crystal size and solubility measurements and isotopic labeling experiments provide insights into the mechanism of attrition-enhanced deracemization and resolution of solid enantiomorphic chiral compounds, and extension to non-racemizing conditions provides a novel methodology for chiral resolution.
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Rational ligand design for the arylation of hindered primary amines guided by reaction progress kinetic analysis.
TL;DR: In this article, the Pd-catalyzed arylation of very hindered α,α,α-trisubstituted primary amines was reported, which was effective in coupling a wide range of functionalized aryl and heteroaryl halides under mild conditions.
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Kinetically guided radical-based synthesis of C(sp3)−C(sp3) linkages on DNA
Jie Wang,Helena Lundberg,Shota Asai,Pedro Martín-Acosta,Jason S. Chen,Stephen P. Brown,William Farrell,Russell Dushin,Christopher J. O’Donnell,Anokha S. Ratnayake,Paul G. Richardson,Zhiqing Liu,Tian Qin,Donna G. Blackmond,Phil S. Baran +14 more
TL;DR: A systematic approach to translating standard organic reactions to a DEL setting through the tactical combination of kinetic analysis and empirical screening with information captured from data mining is described.
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Meteoritic Amino Acids: Diversity in Compositions Reflects Parent Body Histories.
Jamie E. Elsila,José C. Aponte,Donna G. Blackmond,Aaron S. Burton,Jason P. Dworkin,Daniel P. Glavin +5 more
TL;DR: This Outlook reviews recent meteoritic analyses, focusing on variations in abundance, structural distributions, and enantiomeric distributions of amino acids and discussing possible explanations for these observations and the potential for future work.
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Why are BINOL-based monophosphites such efficient ligands in Rh-catalyzed asymmetric olefin hydrogenation?
Manfred T. Reetz,Andreas Meiswinkel,Gerlinde Mehler,Klaus Angermund,Martin Graf,Walter Thiel,Richard Mynott,Donna G. Blackmond +7 more
TL;DR: The present mechanistic study, which includes the NMR characterization of the precatalysts, kinetic measurements with focus on nonlinear effects, and DFT calculations, constitutes a first step in understanding this hydrogenation system.