Elizabeth L. Wilder

TL;DR: The Genotype-Tissue Expression (GTEx) project is described, which will establish a resource database and associated tissue bank for the scientific community to study the relationship between genetic variation and gene expression in human tissues.

TL;DR: Five broad areas are identified that would help propel the field of cellular senescence in tissues and organs forward.

TL;DR: The NIH Roadmap Epigenomics Program was launched to deliver reference epigenomic data from human tissues and cells, develop tools and methods for analyzing the epigenome, discover novel epigenetic marks, develop methods to manipulate the epigenomes, and determine epigenetic contributions to diverse human diseases.

TL;DR: A mechanism for funding biomedical research at NIH that transcends Institute and Center boundaries is bearing fruit and each of the initial Roadmap programs that emerged was designed to achieve defined goals or transition to other sources of support within 10 years.

TL;DR: Almost 4 years ago, one of us (F.S.C.) wrote an Editorial affirming the continued importance of basic research to the National Institutes of Health mission.