David Tabor

TL;DR: The Genotype-Tissue Expression (GTEx) project is described, which will establish a resource database and associated tissue bank for the scientific community to study the relationship between genetic variation and gene expression in human tissues.

TL;DR: The landscape of gene expression across tissues is described, thousands of tissue-specific and shared regulatory expression quantitative trait loci (eQTL) variants are cataloged, complex network relationships are described, and signals from genome-wide association studies explained by eQTLs are identified.

TL;DR: Findings in this nested case-control study are consistent with the hypothesis that HPV infection is the primary cause of cervical neoplasia and support HPV vaccine research to prevent cervical cancer and efforts to develop HPV DNA diagnostic tests.

TL;DR: In this article, the aging gene expression signatures are very tissue specific and enrichment for some well-known aging components such as mitochondria biology is observed in many tissues, and different levels of cross-tissue synchronization of age-related gene expression changes are observed, and some essential tissues (e.g., heart and lung) show much stronger "co-aging" than other tissues based on principal component analysis.

TL;DR: A vast AE resource generated from the GTEx v8 release is presented and the utility of this resource is demonstrated, and an extension of the tool phASER is developed that allows effect sizes of cis -regulatory variants to be estimated using haplotype-level AE data.