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Barbara A. Foster

Researcher at Roswell Park Cancer Institute

Publications -  125
Citations -  20801

Barbara A. Foster is an academic researcher from Roswell Park Cancer Institute. The author has contributed to research in topics: Prostate cancer & Prostate. The author has an hindex of 44, co-authored 114 publications receiving 16632 citations. Previous affiliations of Barbara A. Foster include University of California, San Francisco & Baylor College of Medicine.

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The Genotype-Tissue Expression (GTEx) project

John T. Lonsdale, +129 more
- 29 May 2013 - 
TL;DR: The Genotype-Tissue Expression (GTEx) project is described, which will establish a resource database and associated tissue bank for the scientific community to study the relationship between genetic variation and gene expression in human tissues.
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The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

Kristin G. Ardlie, +132 more
- 08 May 2015 - 
TL;DR: The landscape of gene expression across tissues is described, thousands of tissue-specific and shared regulatory expression quantitative trait loci (eQTL) variants are cataloged, complex network relationships are described, and signals from genome-wide association studies explained by eQTLs are identified.
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The GTEx Consortium atlas of genetic regulatory effects across human tissues

François Aguet, +167 more
- 01 Jan 2020 - 
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Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics.

Alvaro N. Barbeira, +263 more
TL;DR: A mathematical expression is derived to compute PrediXcan results using summary data, and the effects of gene expression variation on human phenotypes in 44 GTEx tissues and >100 phenotypes are investigated.
Journal Article

Characterization of Prostatic Epithelial Cell Lines Derived from Transgenic Adenocarcinoma of the Mouse Prostate (TRAMP) Model

TL;DR: The rationale for establishing multiple cell lines was to isolate cells representing various stages of cellular transformation and progression to androgen-independent metastatic disease that could be manipulated in vitro and, in combination with the TRAMP model, provide a system to investigate therapeutic interventions, such as immunotherapy prior to clinical trials.