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Emilie Vinolo
Researcher at University of Turin
Publications - 4
Citations - 621
Emilie Vinolo is an academic researcher from University of Turin. The author has contributed to research in topics: Cancer & Precision medicine. The author has an hindex of 3, co-authored 4 publications receiving 467 citations.
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Journal ArticleDOI
Interrogating open issues in cancer precision medicine with patient-derived xenografts
Annette T. Byrne,D Alferez,Frédéric Amant,Daniela Annibali,Joaquín Arribas,Andrew V. Biankin,Andrew V. Biankin,Alejandra Bruna,Eva Budinská,Carlos Caldas,David K. Chang,Robert Clarke,Hans Clevers,George Coukos,Virginie Dangles-Marie,S. Gail Eckhardt,Eva González-Suárez,Els Hermans,Manuel Hidalgo,Monika A. Jarzabek,Steven de Jong,Jos Jonkers,Kristel Kemper,Luisa Lanfrancone,Gunhild Mari Mælandsmo,Elisabetta Marangoni,Jean-Christophe Marine,Enzo Medico,Jens Henrik Norum,Héctor G. Palmer,Daniel S. Peeper,Pier Giuseppe Pelicci,Alejandro Piris-Giménez,Sergio Roman-Roman,Oscar M. Rueda,Joan Seoane,Violeta Serra,Laura Soucek,Dominique Vanhecke,Alberto Villanueva,Emilie Vinolo,Andrea Bertotti,Livio Trusolino +42 more
TL;DR: Patient derived xenografts (PDXs) have emerged as an important platform to elucidate new treatments and biomarkers in oncology as mentioned in this paper, and the ability of PDX models to predict clinical outcomes is being improved through mouse humanization strategies and the implementation of co-clinical trials, within which patients and PDXs reciprocally inform therapeutic decisions.
Journal ArticleDOI
PDX-MI: Minimal Information for Patient-Derived Tumor Xenograft Models.
Terrence F. Meehan,Nathalie Conte,Theodore C. Goldstein,Giorgio Inghirami,Mark A. Murakami,Sebastian Brabetz,Zhiping Gu,Jeffrey Wiser,Patrick Dunn,Dale A. Begley,Debra M. Krupke,Andrea Bertotti,Alejandra Bruna,Matthew H. Brush,Annette T. Byrne,Carlos Caldas,Amanda L. Christie,Dominic Clark,Heidi Dowst,Jonathan R. Dry,James H. Doroshow,Olivier Duchamp,Yvonne A. Evrard,Stephane Ferretti,Kristopher K. Frese,Neal Goodwin,Danielle Greenawalt,Melissa A. Haendel,Els Hermans,Peter J. Houghton,Jos Jonkers,Kristel Kemper,Tin Oo Khor,Michael T. Lewis,Kevin C K Lloyd,Jeremy Mason,Enzo Medico,Steven B. Neuhauser,James M. Olson,Daniel S. Peeper,Oscar M. Rueda,Je Kyung Seong,Livio Trusolino,Emilie Vinolo,Robert J. Wechsler-Reya,David M. Weinstock,Alana L. Welm,S. John Weroha,Frédéric Amant,Frédéric Amant,Stefan M. Pfister,Stefan M. Pfister,Marcel Kool,Helen Parkinson,Atul J. Butte,Carol J. Bult +55 more
TL;DR: The PDX models minimal information standard (PDX-MI) is presented, which defines the minimal information for describing the clinical attributes of a patient's tumor, the processes of implantation and passaging of tumors in a host mouse strain, quality assurance methods, and the use ofPDX models in cancer research.
Journal ArticleDOI
Interrogating open issues in cancer medicine with patient-derived xenografts.
Annette T. Byrne,D Alferez,Frédéric Amant,Daniela Annibali,Joaquín Arribas,Andrew V. Biankin,Alejandra Bruna,Eva Budinská,Carlos Caldas,David K. Chang,Robert Clarke,Hans Clevers,George Coukos,Virginie Dangles-Marie,S. Gail Eckhardt,Eva González-Suárez,Els Hermans,Manuel Hidalgo,Monika A. Jarzabek,Steven de Jong,Jos Jonkers,Kristel Kemper,Luisa Lanfrancone,Gunhild Mari Mælandsmo,Elisabetta Marangoni,Jean-Christophe Marine,Enzo Medico,Jens Henrik Norum,Hector G. Palmer,Daniel S. Peeper,Pier Giuseppe Pelicci,Alejandro Piris-Giménez,Sergio Roman-Roman,Oscar M. Rueda,Joan Seoane,Violeta Serra,Laura Soucek,Dominique Vanhecke,Alberto Villanueva,Emilie Vinolo,Andrea Bertotti,Livio Trusolino +41 more
TL;DR: This corrects the article DOI: 10.1038/nrc2016.140 to 10.12.140.
Proceedings ArticleDOI
Abstract A8: The EurOPDX consortium: Sharing patient tumor-derived xenografts for collaborative multicentric preclinical trials.
Emilie Vinolo,Elisabetta Marangoni,Violeta Serra,Frédéric Amant,Andrea Bertotti,Andrew V. Biankin,Anne Lise Børresen-Dale,Alejandra Bruna,Eva Budinská,Annette T. Byrne,Carlos Caldas,David K. Chang,Robert Clarke,Els Hermans,Manuel Hidalgo,Steven de Jong,Jos Jonkers,Pedro Lopez,Gunhild Mari Mælandsmo,Vlad Popovici,Sergio Roman-Roman,Joan Seoane,Livio Trusolino,Alberto Villanueva +23 more
TL;DR: The EurOPDX Consortium will create a pipeline that will greatly accelerate and advance the development of novel therapeutic strategies and their validation for cancer treatment, through more predictive preclinical or "co-clinical" data, and reduce the duplication of efforts in oncology drug development.