V
Vlad Popovici
Researcher at Masaryk University
Publications - 78
Citations - 3635
Vlad Popovici is an academic researcher from Masaryk University. The author has contributed to research in topics: Colorectal cancer & Face detection. The author has an hindex of 23, co-authored 69 publications receiving 3295 citations. Previous affiliations of Vlad Popovici include Geneva College & Swiss Institute of Bioinformatics.
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Journal ArticleDOI
The Microarray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models
Leming Shi,Gregory Campbell,Wendell D. Jones,Fabien Campagne,Zhining Wen,Stephen J. Walker,Zhenqiang Su,Tzu Ming Chu,Federico Goodsaid,Lajos Pusztai,John D. Shaughnessy,André Oberthuer,Russell S. Thomas,Richard S. Paules,Mark R. Fielden,Bart Barlogie,Weijie Chen,Pan Du,Matthias Fischer,Cesare Furlanello,Brandon D. Gallas,Xijin Ge,Dalila B. Megherbi,W. Fraser Symmans,May D. Wang,John Zhang,Hans Bitter,Benedikt Brors,Pierre R. Bushel,Max Bylesjö,Minjun Chen,Jie Cheng,Jing Cheng,Jeff W. Chou,Timothy Davison,Mauro Delorenzi,Youping Deng,Viswanath Devanarayan,David J. Dix,Joaquín Dopazo,Kevin C. Dorff,Fathi Elloumi,Jianqing Fan,Shicai Fan,Xiaohui Fan,Hong Fang,Nina Gonzaludo,Kenneth R. Hess,Huixiao Hong,Jun Huan,Rafael A. Irizarry,Richard S. Judson,Dilafruz Juraeva,Samir Lababidi,Christophe G. Lambert,Li Li,Yanen Li,Zhen Li,Simon Lin,Guozhen Liu,Edward K. Lobenhofer,J. Luo,Wen Luo,Matthew N. McCall,Yuri Nikolsky,Gene Pennello,Roger Perkins,Reena Philip,Vlad Popovici,Nathan D. Price,Feng Qian,Andreas Scherer,Tieliu Shi,Weiwei Shi,Jaeyun Sung,Danielle Thierry-Mieg,Jean Thierry-Mieg,Venkata Thodima,Johan Trygg,Lakshmi Vishnuvajjala,Sue Jane Wang,Jianping Wu,Yichao Wu,Qian Xie,Waleed A. Yousef,Liang Zhang,Xuegong Zhang,Sheng Zhong,Yiming Zhou,Sheng Zhu,Dhivya Arasappan,Wenjun Bao,Anne Bergstrom Lucas,Frank Berthold,Richard J. Brennan,Andreas Buness,Jennifer G. Catalano,Chang Chang,Rong Chen,Yiyu Cheng,Jian Cui,Wendy Czika,Francesca Demichelis,Xutao Deng,Damir Dosymbekov,Roland Eils,Yang Feng,Jennifer Fostel,Stephanie Fulmer-Smentek,James C. Fuscoe,Laurent Gatto,Weigong Ge,Darlene R. Goldstein,Li Guo,Donald N. Halbert,Jing Han,Stephen C. Harris,Christos Hatzis,Damir Herman,Jianping Huang,Roderick V. Jensen,Rui Jiang,Charles D. Johnson,Giuseppe Jurman,Yvonne Kahlert,Sadik A. Khuder,Matthias Kohl,Jianying Li,Li Lee,Menglong Li,Quan Zhen Li,Shao Li,Zhiguang Li,Jie Liu,Ying Liu,Zhichao Liu,Lu Meng,Manuel Madera,Francisco Martinez-Murillo,Ignacio Medina,Joseph Meehan,K. Miclaus,Richard A. Moffitt,David Montaner,Piali Mukherjee,George Mulligan,Padraic Neville,Tatiana Nikolskaya,Baitang Ning,Grier P. Page,Joel S. Parker,R. Mitchell Parry,Xuejun Peng,Ron L. Peterson,John H. Phan,Brian Quanz,Yi Ren,Samantha Riccadonna,Alan H. Roter,Frank W. Samuelson,Martin Schumacher,Joseph D. Shambaugh,Qiang Shi,Richard Shippy,Shengzhu Si,Aaron Smalter,Christos Sotiriou,Mat Soukup,Frank Staedtler,Guido Steiner,Todd H. Stokes,Qinglan Sun,Pei Yi Tan,Rong Tang,Zivana Tezak,Brett T. Thorn,Marina Tsyganova,Yaron Turpaz,S. Vega,Roberto Visintainer,Juergen Von Frese,Charles Wang,Eric Wang,Junwei Wang,Wei Wang,Frank Westermann,James C. Willey,Matthew Woods,Shujian Wu,Nianqing Xiao,Joshua Xu,Lei Xu,Lun Yang,Xiao Zeng,Jialu Zhang,Li Zheng,Min Zhang,Chen Zhao,Raj K. Puri,Uwe Scherf,Weida Tong,Russell D. Wolfinger +201 more
TL;DR: P predictive models for classifying a sample with respect to one of 13 endpoints indicative of lung or liver toxicity in rodents, or of breast cancer, multiple myeloma or neuroblastoma in humans are generated.
Journal ArticleDOI
Distal and proximal colon cancers differ in terms of molecular, pathological, and clinical features.
Edoardo Missiaglia,Bart Jacobs,Giovanni D'Ario,A.F. di Narzo,Charlotte Soneson,Eva Budinská,Vlad Popovici,Loredana Vecchione,Sarah Gerster,Pu Yan,Arnaud Roth,Dirk Klingbiel,Fred T. Bosman,Mauro Delorenzi,Mauro Delorenzi,Sabine Tejpar +15 more
TL;DR: Colorectal carcinoma side is associated with differences in key molecular features, some immediately druggable, with important prognostic effects which are maintained in metastatic lesions, and stratification of patients by side for retrospective and prospective analyses of drug efficacy and prognosis is justified.
Book ChapterDOI
The BANCA database and evaluation protocol
Enrique Bailly-Bailliére,Samy Bengio,Frédéric Bimbot,M. Hamouz,Josef Kittler,Johnny Mariéthoz,Jiri Matas,Kieron Messer,Vlad Popovici,Fabienne Poree,Belén Ruiz,Jean-Philippe Thiran +11 more
TL;DR: A protocol for evaluating verification algorithms on the BANCA database, a new large, realistic and challenging multi-modal database intended for training and testing multi- modal verification systems, is described.
Journal ArticleDOI
Gene expression patterns unveil a new level of molecular heterogeneity in colorectal cancer
Eva Budinská,Eva Budinská,Vlad Popovici,Vlad Popovici,Sabine Tejpar,Giovanni D'Ario,Nicolas Lapique,Katarzyna O. Sikora,Antonio Fabio Di Narzo,Pu Yan,John Graeme Hodgson,Scott L. Weinrich,Fred T. Bosman,Arnaud Roth,Mauro Delorenzi,Mauro Delorenzi +15 more
TL;DR: The proposed subtypes provide a novel perspective on the heterogeneity of CRC and should be further explored retrospectively on existing clinical trial datasets and, when sufficiently robust, be prospectively assessed for clinical relevance in terms of prognosis and treatment response predictive capacity.
Journal ArticleDOI
Identification of a Poor-Prognosis BRAF-Mutant–Like Population of Patients With Colon Cancer
Vlad Popovici,Eva Budinská,Sabine Tejpar,Scott L. Weinrich,Heather Estrella,Graeme Hodgson,Eric Van Cutsem,Tao Xie,Fred T. Bosman,Arnaud Roth,Mauro Delorenzi +10 more
TL;DR: A characteristic pattern of gene expression is associated with and accurately predicts BRAF mutation status and identifies a population of BRAF mutated-like KRAS mutants and double wild-type patients with similarly poor prognosis, suggesting a common biology between these tumors.