E
Erhard Bremer
Researcher at University of Marburg
Publications - 170
Citations - 12681
Erhard Bremer is an academic researcher from University of Marburg. The author has contributed to research in topics: Bacillus subtilis & Ectoine. The author has an hindex of 61, co-authored 164 publications receiving 11488 citations. Previous affiliations of Erhard Bremer include Max Planck Society & University of Konstanz.
Papers
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Journal ArticleDOI
Uptake and synthesis of compatible solutes as microbial stress responses to high-osmolality environments.
Bettina Kempf,Erhard Bremer +1 more
TL;DR: The intracellular amassing of compatible solutes as an adaptive strategy to high-osmolality environments is evolutionarily well-conserved in Bacteria, Archaea, and Eukarya.
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A physiological role for DNA supercoiling in the osmotic regulation of gene expression in S. typhimurium and E. coli
Christopher F. Higgins,Charles J. Dorman,Douglas A. Stirling,Lesley Waddell,Ian R. Booth,Gerhard May,Erhard Bremer +6 more
TL;DR: Evidence that DNA supercoiling plays a key role in the osmotic induction of proU transcription is presented, and mutations in osmZ are highly pleiotropic, affecting expression of a variety of chromosomal genes including ompF, ompC, fimA, and the bgl operon.
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Osmosensing and osmoregulatory compatible solute accumulation by bacteria
Janet M. Wood,Erhard Bremer,Laszlo N. Csonka,Reinhard Kraemer,Bert Poolman,Tiemen van der Heide,Linda Tombras Smith +6 more
TL;DR: The molecular bases for the modulation of gene expression and transport activity by temperature and medium osmolality are under intensive investigation with emphasis on the role of the membrane as an antenna for osmo- and/or thermosensors.
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Small cationic antimicrobial peptides delocalize peripheral membrane proteins
Michaela Wenzel,Alina Iulia Chiriac,Andreas Otto,Dagmar Zweytick,Caroline May,Catherine Schumacher,Ronald Gust,H. Bauke Albada,Maya Penkova,Ute Krämer,Ralf Erdmann,Nils Metzler-Nolte,Suzana K. Straus,Erhard Bremer,Dörte Becher,Heike Brötz-Oesterhelt,Hans-Georg Sahl,Julia E. Bandow +17 more
TL;DR: It is shown that peptide integration into the membrane causes delocalization of essential peripheral membrane proteins essential for respiration and cell-wall biosynthesis, limiting cellular energy and undermining cell- wall integrity.
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Adaptation of Escherichia coli to high osmolarity environments: Osmoregulation of the high-affinity glycine betaine transport system ProU
TL;DR: The properties of the high-affinity glycine betaine transport system ProU and the osmotic regulation of its structural genes are discussed and the importance of compatible solutes for bacteria is discussed.