E
Eric Stern
Researcher at Yale University
Publications - 64
Citations - 4683
Eric Stern is an academic researcher from Yale University. The author has contributed to research in topics: Nanowire & Semiconductor. The author has an hindex of 22, co-authored 63 publications receiving 4332 citations.
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Journal ArticleDOI
Label-free immunodetection with CMOS-compatible semiconducting nanowires
Eric Stern,James F. Klemic,David A. Routenberg,Pauline N. Wyrembak,Daniel B. Turner-Evans,Andrew D. Hamilton,David A. LaVan,Tarek M. Fahmy,Mark A. Reed +8 more
TL;DR: This work reports an approach that uses complementary metal oxide semiconductor (CMOS) field effect transistor compatible technology and hence demonstrates the specific label-free detection of below 100 femtomolar concentrations of antibodies as well as real-time monitoring of the cellular immune response.
Journal ArticleDOI
Importance of the Debye screening length on nanowire field effect transistor sensors.
TL;DR: The appropriate conditions under which the selective binding of macromolecules is accurately sensed with NW-FET sensors are shown.
Journal ArticleDOI
Label-free biomarker detection from whole blood.
Eric Stern,Aleksandar Vacic,Nitin K. Rajan,Jason M. Criscione,Jason Park,Bojan Ilic,David J. Mooney,Mark A. Reed,Tarek M. Fahmy +8 more
TL;DR: This work shows specific and quantitative detection of two model cancer antigens from a 10 uL sample of whole blood in less than 20 minutes and reduces its minimum required sensitivity by effectively pre-concentrating the biomarkers.
Journal ArticleDOI
Combination delivery of TGF-β inhibitor and IL-2 by nanoscale liposomal polymeric gels enhances tumour immunotherapy
Jason Park,Stephen H. Wrzesinski,Stephen H. Wrzesinski,Eric Stern,Michael Look,Jason M. Criscione,Ragy Ragheb,Steven M. Jay,Stacey L. Demento,Atu Agawu,Paula Licona Limon,Anthony F. Ferrandino,David Gonzalez,Ann Habermann,Richard A. Flavell,Richard A. Flavell,Tarek M. Fahmy,Tarek M. Fahmy +17 more
TL;DR: N nanoscale liposomal polymeric gels (nanolipogels; nLGs) of drug-complexed cyclodextrins and cytokine-encapsulating biodegradable polymers that can deliver small hydrophobic molecular inhibitors and water-soluble protein cytokines in a sustained fashion to the tumour microenvironment significantly delayed tumour growth and increased survival of tumour-bearing mice.
Journal ArticleDOI
Role of sustained antigen release from nanoparticle vaccines in shaping the T cell memory phenotype.
Stacey L. Demento,Weiguo Cui,Jason M. Criscione,Eric Stern,Jacob E. Tulipan,Susan M. Kaech,Tarek M. Fahmy +6 more
TL;DR: This study highlights the importance of sustained antigen release mediated by particulate platforms and its role in the long-term appearance of effector memory cellular response and compares the efficacy of Vesicular and solid biodegradable polymer platforms.