E
Erik F. Kot
Researcher at Moscow Institute of Physics and Technology
Publications - 11
Citations - 34
Erik F. Kot is an academic researcher from Moscow Institute of Physics and Technology. The author has contributed to research in topics: Medicine & Transmembrane domain. The author has an hindex of 3, co-authored 3 publications receiving 12 citations. Previous affiliations of Erik F. Kot include Russian Academy of Sciences.
Papers
More filters
Journal ArticleDOI
Phase Transitions in Small Isotropic Bicelles.
Erik F. Kot,Erik F. Kot,Sergey A. Goncharuk,Sergey A. Goncharuk,Alexander S. Arseniev,Alexander S. Arseniev,Konstantin S. Mineev,Konstantin S. Mineev +7 more
TL;DR: It is demonstrated clearly that phase transitions take place even in the smallest bicelles that are applicable for structural studies of membrane proteins by solution NMR spectroscopy, drawing a thick line under the long-lasting argument about the relevance of small isotropic bICElles.
Journal ArticleDOI
Behavior of Most Widely Spread Lipids in Isotropic Bicelles
TL;DR: It is stated that SM exclusively, and PG/PS in mixtures with zwitterionic lipids can form small isotropic bicelles, which reproduce the key features of lipid behavior in bilayers.
Journal ArticleDOI
Oligomerization analysis as a tool to elucidate the mechanism of EBV latent membrane protein 1 inhibition by pentamidine
Erik F. Kot,Yibo Wang,Sergey A. Goncharuk,Bo Zhang,Alexander S. Arseniev,Xiaohui Wang,Xiaohui Wang,Konstantin S. Mineev +7 more
TL;DR: An NMR-based approach is proposed to treat the complex oligomerization equilibria with slow conformational exchange and suggests that D150 is likely charged in the full-length LMP1 under native conditions.
Journal ArticleDOI
Psychedelics promote plasticity by directly binding to BDNF receptor TrkB
Rafael Moliner,Mykhailo Girych,Cecilia A. Brunello,Vera Kovaleva,Caroline Biojone,Giray Enkavi,Lina Antenucci,Erik F. Kot,Sergey A. Goncharuk,Katja Kaurinkoski,Senem Merve Fred,Lauri Elsilä,Sven Sakson,Cecilia Cannarozzo,Cassiano R.A.F. Diniz,Nina Seiffert,Anna Rubiolo,H M Haapaniemi,Elina I. Nagaeva,Tiina Öhman,Tomasz Róg,Esko Kankuri,Marçal Vilar,Markku Varjosalo,Esa R. Korpi,Perttu Permi,Konstantin S. Mineev,Mart Saarma,Ilpo Vattulainen,Plinio C. Casarotto,Eero Castrén +30 more
TL;DR: This article showed that LSD and psilocin directly bind to TrkB with affinities 1,000-fold higher than those for other antidepressants, and that psychedelics and antidepressants bind to distinct but partially overlapping sites within the transmembrane domain of TrkB dimers.
Journal ArticleDOI
The architecture of transmembrane and cytoplasmic juxtamembrane regions of Toll-like receptors
Fedor Kornilov,A. V. Shabalkina,Cong Lin,Pavel E. Volynsky,Erik F. Kot,Alexey L Kayushin,Vladislav A. Lushpa,Marina V. Goncharuk,Alexander S. Arseniev,Sergey A. Goncharuk,Xiaohui Wang,Konstantin S. Mineev +11 more
TL;DR: In this article , the spatial structures of transmembrane and cytoplasmic juxtamembrane regions of TLR2, TLR3 and TLR5 were investigated using solution NMR spectroscopy and computer simulations.