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Eugene Braunwald

Researcher at Brigham and Women's Hospital

Publications -  1758
Citations -  278949

Eugene Braunwald is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Myocardial infarction & TIMI. The author has an hindex of 230, co-authored 1711 publications receiving 264576 citations. Previous affiliations of Eugene Braunwald include Boston University & University of California, San Francisco.

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Contractile State of the Heart Characterized by Force-Velocity Relations in Variably Afterloaded and Isovolumic Beats

TL;DR: It was suggested that determination of relations between tension and the velocity of shortening in the intact left ventricle of the dog expands traditional definitions of ventricular performance, and that estimation of changes in maximum velocity as well as maximum strength relative to muscle length provides direct information concerning alterations in the contractile state of the intact heart.
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Tissue plasminogen activator.

TL;DR: TISSUE plasminogen activator (t-PA) is a naturally occurring protein that catalyzes the conversion of the inactive proenzyme plAsminogen into the active serine protease plasmine.
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Studies on Cardiac Dimensions in Intact, Unanesthetized Man

TL;DR: The effects of rotation of the heart in the sagittal plane during the cardiac and respiratory cycles were determined precisely and indicated that an increase in myocardial contractility occurs during muscular exercise in man.
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Detection of acute changes in circulating troponin in the setting of transient stress test-induced myocardial ischaemia using an ultrasensitive assay: results from TIMI 35

TL;DR: Transient stress test-induced myocardial ischaemia is associated with a quantifiable increase in circulating troponin that is detectable with a novel, ultrasensitive TnI assay.
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Potential benefits of late reperfusion of infarcted myocardium. The open artery hypothesis.

TL;DR: Hirudin reduces reocclusion compared to heparin following thrombolysis in acute myocardial infarction: results of the TIMI-5 trial.