E
Eugene Braunwald
Researcher at Brigham and Women's Hospital
Publications - 1758
Citations - 278949
Eugene Braunwald is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Myocardial infarction & TIMI. The author has an hindex of 230, co-authored 1711 publications receiving 264576 citations. Previous affiliations of Eugene Braunwald include Boston University & University of California, San Francisco.
Papers
More filters
Journal ArticleDOI
Circadian variation in the onset of unstable angina and non-Q-wave acute myocardial infarction (the TIMI III Registry and TIMI IIIB).
Christopher P. Cannon,Carolyn H. McCabe,Peter Stone,Mark Schactman,Bruce Thompson,Pierre Theroux,Robert S. Gibson,Ted Feldman,Neal S. Kleiman,Geoffrey H. Tofler,James E. Muller,Bernard R. Chaitman,Eugene Braunwald +12 more
TL;DR: Previous studies suggest that circadian variation exists in the onset of the full spectrum of myocardial ischemic syndromes in unstable angina and non-Q-wave AMI, and the TIMI IIIB trial confirmed this.
Journal ArticleDOI
Galectin-3 and the Development of Heart Failure after Acute Coronary Syndrome: Pilot Experience from PROVE IT-TIMI 22
E. Wilson Grandin,Petr Jarolim,Sabina A. Murphy,Lea Ritterova,Christopher P. Cannon,Eugene Braunwald,David A. Morrow +6 more
TL;DR: The finding that galectin-3 is associated with the risk of developing HF following ACS adds to emerging evidence supporting galectIn-3 as a biomarker of adverse remodeling contributing to HF as well as a potential therapeutic target.
Journal ArticleDOI
Relationship between uncontrolled risk factors and C-reactive protein levels in patients receiving standard or intensive statin therapy for acute coronary syndromes in the PROVE IT-TIMI 22 trial.
Kausik K. Ray,Christopher P. Cannon,Richard Cairns,David A. Morrow,Nader Rifai,Ajay J. Kirtane,Carolyn H. McCabe,Allan M. Skene,C. Michael Gibson,Paul M. Ridker,Eugene Braunwald,Prove It-Timi Investigators +11 more
TL;DR: Even among patients receiving intensive statin therapy, a lower CRP level was observed in patients with the fewest coronary risk factors present, suggesting that control of multiple risk factors may be a means to further achieve lowerCRP levels.
Journal ArticleDOI
Prosthetic replacement of the mitral valve. Preoperative and postoperative clinical and hemodynamic assessments in 100 patients.
TL;DR: Mitral valve replacement provides gratifying symptomatic and hemodynamic improvement in patients with mitral regurgitation or calcific mitral stenosis, and operation is indicated only in severely disabled patients in whom life expectancy is limited.
Journal ArticleDOI
Invasive versus conservative strategies in unstable angina and non\NQ-wave myocardial infarction following treatment with tirofiban: rationale and study design of the international TACTICS-TIMI 18 trial ☆
Christopher P. Cannon,William S. Weintraub,Laura A. Demopoulos,Deborah H. Robertson,Glenn J. Gormley,Eugene Braunwald +5 more
TL;DR: The Treat Angina with Aggrastat and determine Cost of Therapy with an Invasive or Conservative Strategy (TACTICS-TIMI 18) trial is an international, multicenter, randomized trial that is evaluating the clinical efficacy of early invasive and early conservative treatment strategies in patients with unstable angina or non–Q-wave AMI treated with tirofiban, heparin, and aspirin.