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Eugene Braunwald
Researcher at Brigham and Women's Hospital
Publications - 1758
Citations - 278949
Eugene Braunwald is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Myocardial infarction & TIMI. The author has an hindex of 230, co-authored 1711 publications receiving 264576 citations. Previous affiliations of Eugene Braunwald include Boston University & University of California, San Francisco.
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Journal ArticleDOI
Effects of pravastatin on mortality in patients with and without coronary heart disease across a broad range of cholesterol levels. The Prospective Pravastatin Pooling project.
John Simes,Curt D. Furberg,Eugene Braunwald,Barry R. Davis,Ian Ford,Andrew Tonkin,James Shepherd +6 more
TL;DR: Treatment with pravastatin over 5 years reduces all-cause mortality and coronary mortality in patients with and those without a history of coronary heart disease, and the size of the benefit was related principally to the baseline risk.
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Mechanism of increase of myocardial oxygen uptake produced by catecholamines.
TL;DR: It is concluded that while large doses of catecholamines can increase oxidative metabolism of the nonbeating heart by a small amount, the increases of MVo 2 produced by catechlamines in the beating heart are due in large part to the hemodynamic alterations which the amines induce.
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Prolonged abnormalities of myocardium salvaged by reperfusion.
Robert A. Kloner,Laurence W.V. DeBoer,John R. Darsee,Joanne S. Ingwall,Sharon L. Hale,J. Tumas,Eugene Braunwald +6 more
TL;DR: Brief periods of myocardial ischemia are not associated with necrosis but result in functional, biochemical, and ultrastructural abnormalities, which are present for at lest 3 days after coronary reperfusion.
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Prognosis after cardiac arrest due to ventricular tachycardia or ventricular fibrillation associated with acute myocardial infarction (The MILIS study)
Geoffrey H. Tofler,Peter Stone,James E. Muller,John D. Rutherford,Stefan N. Willich,Nancy Gustafson,W. Kenneth Poole,Burton E. Sobel,James T. Willerson,Thomas S. Robertson,Eugene R. Passamani,Eugene Braunwald +11 more
TL;DR: Patients with confirmed AMI diagnosed with cardiac arrest due to ventricular tachycardia or ventricular fibrillation in acute myocardial infarction had a higher mortality than patients in whom VT/VF occurred.
Journal ArticleDOI
Edoxaban vs. warfarin in patients with atrial fibrillation on amiodarone: a subgroup analysis of the ENGAGE AF-TIMI 48 trial
Jan Steffel,Robert P. Giugliano,Eugene Braunwald,Sabina A. Murphy,Dan Atar,Hein Heidbuchel,Alan John Camm,Elliott M. Antman,Christian T. Ruff +8 more
TL;DR: Patients randomized to the LDE treated with amiodarone at the time of randomization demonstrated a significant reduction in ischaemic events vs. warfarin when compared with those not on amioarone, while preserving a favourable bleeding profile.