E
Eugene Braunwald
Researcher at Brigham and Women's Hospital
Publications - 1758
Citations - 278949
Eugene Braunwald is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Myocardial infarction & TIMI. The author has an hindex of 230, co-authored 1711 publications receiving 264576 citations. Previous affiliations of Eugene Braunwald include Boston University & University of California, San Francisco.
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Journal ArticleDOI
Efficacy and Safety of Vorapaxar as Approved for Clinical Use in the United States
Giulia Magnani,Marc P. Bonaca,Eugene Braunwald,Anthony J. Dalby,Keith A.A. Fox,Sabina A. Murphy,Jose C. Nicolau,Ton Oude Ophuis,Benjamin M. Scirica,Jindrich Spinar,Pierre Théroux,David A. Morrow +11 more
TL;DR: In patients with prior MI or PAD who have not had a previous stroke or TIA, vorapaxar added to standard therapy is effective for long‐term secondary prevention of thrombotic CV events, while increasing moderate or severe bleeding.
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Angiographic predictors of reocclusion after thrombolysis: results from the Thrombolysis in Myocardial Infarction (TIMI) 4 trial.
C. Michael Gibson,Christopher P. Cannon,Robert N. Piana,Jeffrey A. Breall,Jeffrey A. Breall,Barry M. Sharaf,Barry M. Sharaf,Margaret Flatley,Margaret Flatley,Barbara Alexander,Barbara Alexander,Daniel J. Diver,Daniel J. Diver,Carolyn H. McCabe,Greg C. Flaker,Greg C. Flaker,Donald S. Baim,Donald S. Baim,Eugene Braunwald +18 more
TL;DR: Angiographic variables, such as the presence of TIMI grade 2 flow, ulceration, collateral vessels and greater percent diameter stenosis at 90 min after thrombolytic therapy, are associated with significantly higher rates of infarct-related artery reocclusion by 18 to 36 h and may aid in identifying the subset of patients who are at significantly higher risk of early reoc inclusion.
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Rapid Sequential Visualization of the Heart and Great Vessels in Man Using the Wide-Field Anger Scintillation Camera Radioisotope-Angiography Following the Injection of Technetium-99m
TL;DR: The radioisotope-angiocardiogram provides a new approach for visualization of the cardiovascular system, does not require the use of radiopaque medium, is safer than angiography, and does not disturb circulatory function.
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Impact of diabetes mellitus on epicardial and microvascular flow after fibrinolytic therapy
Brad G. Angeja,James A. de Lemos,Sabina A. Murphy,Susan J. Marble,Elliott M. Antman,Christopher P. Cannon,Eugene Braunwald,C. Michael Gibson +7 more
TL;DR: Thrombolysis and adjunctive/rescue PCI achieved equal rates of epicardial flow in patients with and without diabetes, however, diabetic patients had less complete ST-segment resolution, suggesting impaired microvascular flow.
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Vorapaxar in Patients With Diabetes Mellitus and Previous Myocardial Infarction Findings From the Thrombin Receptor Antagonist in Secondary Prevention of Atherothrombotic Ischemic Events-TIMI 50 Trial
Matthew A. Cavender,Benjamin M. Scirica,Marc P. Bonaca,Dominick J. Angiolillo,Anthony J. Dalby,Mikael Dellborg,João Morais,Sabina A. Murphy,Ton Oude Ophuis,Michal Tendera,Eugene Braunwald,David A. Morrow +11 more
TL;DR: In patients with previous MI and DM, the addition of vorapaxar to standard therapy significantly reduced the risk of major vascular events with greater potential for absolute benefit in this group at high risk of recurrent ischemic events.